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Springer Nature1
Journal
Histochemistry and Cell Biology1
Publication Year
20231
Hiten Patel results 1 · Newest (Page 1/1, per page 25)
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Author: Hiten Patel ×Clear All Filters
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Opposite changes in the expression of clathrin and caveolin-1 in normal and cancerous human prostate tissue: putative clathrin-mediated recycling of EGFRNARA Subscribed
Histochemistry and Cell Biology · 2023 · Vol. 159 · Issue 6 · Springer
Boyu Xie; Hawra Zuhair; Rui Henrique; Michael Millar; Timothy Robson; Christopher Thrasivoulou; Kerry Dickens; Jane Pendjiky; Asif Muneer; Hiten Patel; Aamir Ahmed
Endocytosis, an important macromolecule uptake process in cells, is known to be dysregulated in cancer. Clathrin and caveolin-1 proteins play a major role in receptor-mediated endocytosis. We have used a quantitative, unbiased and semi-automated method to measure in situ protein expression of clathrin and caveolin-1 in cancerous and paired normal (cancer adjacent, non-cancerous) human prostate tissue. There was a significant (...
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