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The functional and molecular definition of progenitors giving rise to blood vessel endothelium in vivo remains disputed. Upon investigating the overlap of seemingly divergent reports currently defining putative endothelial progenitor cells (EPCs) using single-cell RNA-sequencing and flow cytometry, Protein C Receptor (PROCR) and Platelet-Derived Growth Factor Receptor Alpha (PDGFRA) largely overlapped with previously character...
While previous research on environmental efficiency examines data from the annual reports of shipping companies, this study takes a novel approach. It applies data envelopment analysis (DEA) and backcasting theory to assess environmental efficiency and plan the transition to cleaner fuels among global container shipping companies. Companies are categorized as first movers, second movers, and last movers based on their environm...
Distinct roles of SOX9 in self-renewal of progenitors and mesenchymal transition of the endotheliumNARA Subscribed
Regenerative capabilities of the endothelium rely on vessel-resident progenitors termed endothelial colony forming cells (ECFCs). This study aimed to investigate if these progenitors are impacted by conditions (i.e., obesity or atherosclerosis) characterized by increased serum levels of oxidized low-density lipoprotein (oxLDL), a known inducer of Endothelial-to-Mesenchymal Transition (EndMT). Our investigation focused on under...