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A practice guideline for therapeutic drug monitoring of mycophenolic acid for solid organ transplantsNARA Subscribed
Mycophenolic acid (MPA), the active moiety of both mycophenolate mofetil (MMF) and enteric-coated mycophenolate sodium (EC-MPS), serves as a primary immunosuppressant for maintaining solid organ transplants. Therapeutic drug monitoring (TDM) enhances treatment outcomes through tailored approaches. This study aimed to develop an evidence-based guideline for MPA TDM, facilitating its rational application in clinical settings. Th...
Wave energy, as a renewable energy source, plays a significant role in sustainable energy development. This study focuses on a dual-chamber offshore oscillating water column (OWC) wave energy device and performs numerical simulations to analyze the influence of chamber geometry on hydrodynamic characteristics and wave energy conversion efficiency. Unlike existing studies primarily focused on single-chamber configurations, the...
Rising sea level caused by global climate change may increase extreme sea level events, flood low-lying coastal areas, change the ecological and hydrological environment of coastal areas, and bring severe challenges to the survival and development of coastal cities. Hong Kong is a typical economically and socially developed coastal area. However, in such an important coastal city, the mechanisms of local sea-level dynamics and...