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Translational Stroke Research · 2021 · Vol. 12 · Issue 5 · Springer
Monocytes recruitment from the blood to inflamed tissues following ischemic stroke is an important immune response to wound healing and tissue repair. Mouse monocytes can be endogenously divided into two distinct populations: pro-inflammatory or classical monocytes that express CCR2 high CX3CR1 low and circulate in blood, and anti-inflammatory or non-classical monocytes that express CCR2 low CX3CR1 high and patrol locally. In...