Purpose In vivo imaging of adult zebrafish remains technically challenging due to loss of optical transparency and the lack of standardized molecular imaging protocols. The development of reliable radiotracer delivery and acquisition parameters is essential for improving imaging reproducibility and translational relevance. Methods Adult zebrafish with hepatobiliary tumor models were imaged using an integrated PET/MR system fol...

Nervous necrosis virus (NNV) is the causative agent of viral nervous necrosis, otherwise known as viral encephalopathy and retinopathy in larval and juvenile marine fish worldwide. The pandemic outbreaks have caused nearly 100% mortality in hatcheries, leading to significant economic losses in the aquaculture industry. Since NNV attacks the insufficient immune competence fish at early developmental stages, there is an urgent n...

Background/Aim Breast cancer (BC) remains a major health threat, highlighting the need for accessible screening. Characteristics of the cardiovascular system can be altered in BC patients. This study explored a noninvasive method combining arterial pulse-waveform analysis and classification to compare arterial pulse-waveform characteristics between BC patients ( n = 51)) and age-matched controls ( n = 76)). Methods From one-mi...

Major depressive disorder (MDD) is a major public health issue worldwide. It not only causes an increased socio-economic burden, but also negatively affects personal lives. It has been shown that depression leads to impairments in synaptic plasticity, such as impaired long-term potentiation (LTP) in the prefrontal cortex (PFC). A recent study reported that administration of agomelatine, a melatonin receptor agonist and 5-hydro...