Background Radiation esophagitis is a common adverse effect of radiotherapy for head and neck cancers, and is marked by irreversible damage and fibrosis of esophageal muscle tissue. Although mesenchymal stem cell (MSC) therapy is emerging as a promising approach for tissue regeneration, clinical translation remains challenging due to issues with cell viability and differentiation in vivo. This study evaluates the regenerative...

Polyester microfibers (MF) are widespread in aquatic environments and increasingly recognized as an emerging factor affecting fish physiology. This study aimed to investigate the effects of intestinal accumulation of MF on gut tissue and cellular alterations, as well as on the HPG axis and oocyte maturation in adult female zebrafish. Adult female zebrafish were exposed to environmentally relevant concentrations of MF (1000 and...