Total plasma N -glycans alter in disease states, with few studies focused on COVID-19. A discovery cohort of 310 COVID-19 patients, replicated with 97 COVID-19 patients and tested with 100 COVID-19 patients, was used to unearth the N -glycans capable of distinguishing infection, as well as prognosis of intensive care unit (ICU) admission and mortality. All significant bisected glycans were decreased in patients compared to con...

Public and private interest in life cycle assessment (LCA) has grown as environmental disclosure norms tighten, driving demand for decision-relevant assessment early in technological development cycles. Early-stage LCA has the potential to guide design choices, steer innovation, and mitigate lock-in of adverse environmental impacts. However, many aspects of early-stage LCA practice remain unsettled. We convened experts in a se...

Purpose Unrecognized contraindications pose risks for adverse drug reactions, hospitalizations or death. Clinical decision support systems (CDSS) aim to mitigate medication-related harm, particularly originating from contraindications. However, many CDSS provide limited benefit, as they focus largely on singular risk situations such as drug-drug interactions and often generate alerts of limited clinical relevance. Comprehensiv...

Social structures and habitat configuration influence inbreeding in wild populations. In harem‐forming, female‐defence polygynous equids, social organization promotes inbreeding avoidance, but this has not been studied in fission–fusion, resource‐defence equid species. Because reproduction depends on solitary males establishing territories near resources, shifts in resource distribution are expected to affect mating patterns a...

Achieving sustainability requires collective action by diverse stakeholders, facilitated by knowledge systems that integrate scientific, policy, and locally tested, place-based practical insights. As collective action and knowledge systems are usually analyzed separately, this paper explicitly examines this relationship, assessing the role of knowledge in shaping collective action within a network of 32 sustainability initiati...