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Association mapping desiccation resistance within chromosomal inversions in the African malaria vector Anopheles gambiaeNARA Subscribed
Inversion polymorphisms are responsible for many ecologically important phenotypes and are often found under balancing selection. However, the same features that ensure their large role in local adaptation—especially reduced recombination between alternate arrangements—mean that uncovering the precise loci within inversions that control these phenotypes is unachievable using standard mapping approaches. Here, we take advantage...
Sequence variation at the intron‐1 of the voltage‐gated sodium channel gene in Anopheles gambiae M‐ and S‐forms from Cameroon was assessed to explore the number of mutational events originating knockdown resistance ( kdr ) alleles. Mosquitoes were sampled between December 2005 and June 2006 from three geographical areas: (i) Magba in the western region; (ii) Loum, Tiko, Douala, Kribi, and Campo along the Atlantic coast; and (i...
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