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Journal: GeroScience ×Author: Ian Harding ×Clear All Filters
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GeroScience · 2026 · Springer
Hypertension in midlife is associated with increased dementia risk, yet its relationship with early pathological changes of Alzheimer’s disease and related dementias (ADRD) remains unclear. Unlike office blood pressure (BP), 24-h ambulatory BP (ABPM) may better reflect cardiovascular risk, but associations between 24-h BP measures with ADRD biomarkers are unknown. This cross-sectional study examined associations between BP and...
GeroScience · 2025 · Vol. 48 · Issue 2 · Springer
Individual imaging and fluid biomarkers provide insights into specific components of brain health, but integrated multimodal approaches are necessary to capture the complex, interrelated biological systems that contribute to brain homeostasis and neurodegenerative disease. Using data from the Brain and Cognitive Health (BACH) cohort study ( N = 127; mean age = 67 years, 68% women), we performed an exploratory factor analysis t...