Authentication of dairy product composition is vital for consumer protection and food safety. This study validated 4 real-time PCR methods targeting mitochondrial DNA from cattle, sheep, goat, and total mammals in a collaborative ring trial. Twelve well-characterised dairy samples – including milk, yoghurt, Picodon-type cheese, and Feta-type cheese ‒ were produced from sheep and goat milk with 1–33.3% cow milk admixture for us...

Pancreatic stellate cells (PSCs) that can co-metastasize with cancer cells shape the tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC) by producing an excessive amount of extracellular matrix. This leads to a TME characterized by increased tissue pressure, hypoxia, and acidity. Moreover, cells within the tumor secrete growth factors. The stimuli of the TME trigger Ca 2+ signaling and cellular Na + loading...