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Application of Fibronectin-Coated Microparticles for Isolation of Human iPSC-Derived MSCsNARA Subscribed
BACKGROUND : Bone marrow–derived MSCs (BMMSCs) are limited by availability, donor variability, and age-related decline, highlighting the need for alternative MSC sources. Induced pluripotent stem cells (iPSCs) offer a scalable solution. This study introduces a novel three-dimensional culture platform based on fibronectin (FN)-coated microparticles to efficiently derive and expand human iPSC-derived MSCs (iMSCs). METHODS : The...
Elf18-induced Long Noncoding RNA 25 positively regulates the pathogen defense-related CYP82C2 expression in ArabidopsisNARA Subscribed
Long noncoding RNAs (lncRNAs) are emerging as important regulators of gene expression during plant immune responses. In this study, we identified a novel lncRNA, ELF18-INDUCED LONG NONCODING RNA 25 ( ELENA25 ), located in the intergenic region between AT4G31960 and CYTOCHROME P450, family 82, subfamily C, polypeptide 2 ( CYP82C2 ) in Arabidopsis. ELENA25 was initially identified through custom lncRNA microarray data. Here, its...
We comprehensively analyzed sediments obtained from an archeological excavation. A trench sediment profile of Maedun Cave (MC), South Korea, was analyzed geoarchaeologically. Multi‐proxy analyses (palynomorphs, grain size, magnetic susceptibility, animal bones and artifacts) reflected the vegetation, hydroclimate and lives of prehistoric people at Marine Isotope Stage (MIS) 3 (ca. 40–30k cal a bp ) in the early Late Paleolithi...