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Environmental Science and Pollution Research · 2024 · Vol. 31 · Issue 7 · Springer
Maternal exposure to fine particulate matter (PM 2.5 ) is associated with adverse pregnancy and neonatal health outcomes. To explore the mechanism, we performed mRNA sequencing of neonatal cord blood. From an ongoing prospective cohort, Air Pollution on Pregnancy Outcome (APPO) study, 454 pregnant women from six centers between January 2021 and June 2022 were recruited. Individual PM 2.5 exposure was calculated using a time-we...
Genes & Genomics · 2022 · Vol. 44 · Issue 6 · Springer
Background Freshwater endemism is thought to have been formed through the vicariance of connected water systems or the process by which ancestral populations colonized specific areas. The Korean Peninsula is well recognized for its high level of freshwater endemism with about 40% of freshwater fish species being endemic. Objective In this study, we attempted to reconstruct the process of speciation and phylogenetic dispersal o...
Molecular Neurobiology · 2019 · Vol. 56 · Issue 5 · Springer
Impaired neurogenesis has been associated with several brain disorders, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). The role of peroxiredoxin 6 (PRDX6) in neurodegenerative diseases is very controversial. To demonstrate the role of PRDX6 in neurogenesis, we compared the neurogenesis ability of PRDX6-overexpressing transgenic (Tg) mice and wild-type mice and studied the involved molecular mechanisms. We showe...