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We aim to elucidate how miRNAs regulate the mRNA signature of atrial fibrillation (AF), to gain mechanistic insight and identify candidate targets for future therapies. We present combined miRNA–mRNA sequencing using atrial tissues of patient without AF ( n = 22), with paroxysmal AF ( n = 22) and with persistent AF ( n = 20). mRNA sequencing previously uncovered upregulated epithelial to mesenchymal transition, endothelial cel...
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