The cannabinoid receptor type 2 (CB2R), primarily expressed in microglia, the brain’s resident immune cells, acts as a central regulator of neuroinflammatory responses. When CB2R is activated, it triggers anti-inflammatory signaling, making it a promising target for modulating microglial function in neuroinflammatory diseases. The ketone body, β-hydroxybutyrate (BHB), is gaining attention as a therapeutic agent for neurodegene...

Forest diversity is a multidimensional concept comprising different components such as species diversity, functional diversity, structural diversity and genetic diversity. These diverse elements are recognised as being connected to the health and functioning of forest ecosystems and human well-being. However, information on forest diversity at broad spatial scales is scarce. Thus, the primary goal of this study is to quantify...

Frontotemporal dementia (FTD) is a neurodegenerative disease characterized by significant clinical and genetic heterogeneity, with approximately 40% of cases linked to hereditary genetic mutations, including MAPT , GRN , and C9ORF72 . Recently, microRNAs (miRNAs) have emerged as key regulators of cellular processes related to neurodegeneration and as potential biomarkers for FTD. However, their relevance in presymptomatic stag...

The seagrass ecosystems of the Tropical Northwestern Atlantic (TNA) host three described species of sea anemones in the genus Bunodeopsis Andres, 1881 (Enthemonae: Metridioidea: Acuticulata): B. antilliensis , B. globulifera , and B. pelagica . Due to their small size and nocturnal nature, many aspects of their basic biology and distribution remain unknown. To investigate their ecology and distribution, we surveyed five TNA ec...