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Springer Nature1
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Molecular Biology Reports1
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20201
Issa Konate results 1 · Newest (Page 1/1, per page 25)
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Genetic polymorphism of drug metabolism enzymes (GSTM1, GSTT1 and GSTP1) in the healthy Malian populationNARA Subscribed
Molecular Biology Reports · 2020 · Vol. 47 · Issue 1 · Springer
Yaya Kassogue; Brehima Diakite; Oumar Kassogue; Issa Konate; Kadidiatou Tamboura; Zoumana Diarra; Hind Dehbi; Sellama Nadifi; Cheick Bougadari Traore; Sounkalo Dao; Seydou Doumbia; Guimogo Dolo
Glutathione S-transferase genes, known to be highly polymorphic, are implicated in the process of phase II metabolism of many substrates, including xenobiotics, anticancer and anti-infective drugs. The detoxification activity is linked to individual genetic makeup. Therefore, the identification of alleles and genotypes in these genes within a population may help to better design genetic susceptibility and pharmacogenetic studi...
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