Objectives This study aimed to produce an engineered recombinant laccase from extremophilic Halalkalibacterium halodurans C-125 (Lac- HhC-125) with higher protein yield, into a more active conformation and with properties that meet the fundamental needs of biotechnological application. Results The rLac- HhC125 was partially purified by size exclusion chromatography and concentrated by ultrafiltration (10 kDa) with a yield of 5...