Cyprinid herpesvirus 3 (Cy HV ‐3) is the aetiological agent of a serious infective, notifiable disease affecting common carp and varieties. In survivors, infection is generally characterized by a subclinical latency phase with restricted viral replication. The Cy HV ‐3 genome is difficult to detect in such carrier fish that represent a potential source of dissemination if viral reactivation occurs. In this study, the analytica...

A betanodavirus associated with a massive mortality was isolated from larvae of tilapia, Oreochromis niloticus , maintained in fresh water at 30 °C . Histopathology revealed vacuolation of the nervous system, suggesting an infection by a betanodavirus. The virus was identified by indirect fluorescent antibody test in the SSN1 cell line and further characterized by sequencing of a PCR product. Sequencing of the T4 region of the...

Sleeping disease (SD) is a serious disease of rainbow trout, Oncorhynchus mykiss , reared in fresh water caused by sleeping disease virus (SDV). In this study a detailed clinical, histological, virological and serological description of the experimental reproduction of SD in 1‐year‐old rainbow trout exposed to SDV was carried out. Two hundred disease‐free fish were intraperitoneally inoculated with a SDV isolate and 100 fish w...