Allostatic load measures the physiological consequences of stress and is associated with disease outcomes. Clinical use of allostatic load is limited, in part, because its calculation requires biomarkers not routinely measured in clinical care. Presently, we evaluated associations between high allostatic load and depression as co-occurring consequences of stress among a cohort representing population subgroups largely excluded...

The turnover rate of microbial cells drops steeply by increasing depth in the seabed, in accordance with the decreasing rate of organic matter mineralization. Bacterial endospore formation and germination may take place concurrently, yet their coupling to the mineralization rates during burial is poorly understood. We used high‐resolution 14 C‐dating of coring sites on the Peru Margin to show that the upper 8.5 m of sediment h...

Danish coastal waters were severely affected by eutrophication in the 1980s, prompting the implementation of national nutrient reduction plans. The aim of this study was to explore the recovery of Danish coastal waters and report trends for selected indicators of eutrophication. Dissolved inorganic nitrogen (DIN), dissolved inorganic phosphorus (DIP), chlorophyll a, light penetration depth, eelgrass main depth limit, a benthic...

The combined effects of multiple pressures pose critical threats to marine ecosystems. As an initial spatial assessment of cumulative pressures in the Skagerrak, we mapped where multiple pressures coincided with sensitive habitats and species, combining recent spatial data sets on 20 pressures and 39 habitats and species. The spatial data were linked with sensitivity weights obtained with a novel partly data-driven method. We...

Background and aims In highly weathered soils of central Amazonia, where nutrients such as phosphorus (P) and base cations are scarce, fertilization experiments have demonstrated above- and belowground effects on total net primary productivity (NPP). This study examined how fine root stocks and turnover responded to added nutrients over a two-year period. We predicted that adding a limiting nutrient would decrease fine root st...

Although interest in biomarkers of biological aging is growing, consensus on reliable, non-invasive indicators remains limited. Endotrophin, a bioactive fragment released during collagen type VI formation, reflects fibroblast activation and extracellular matrix remodeling and has been linked to chronic diseases, metabolic dysfunction, and inflammation. Whether circulating endotrophin also captures aging-related phenotypes and...

Although aging is a universal event, some individuals are able to achieve extreme longevity. The Long-Life Family Study (LLFS) enrolls participants from families enriched with long-lived individuals, serves as a valuable dataset for studying ageing phenotypes and identify potential intervention targets. We analyzed the association between age at blood draw and 16,284 RNAseq-based blood transcriptomic data from 2,167 LLFS parti...

Dispersal is one of the most important aspects of animal behavior and can have far‐reaching consequences for organismal ecology and evolution. Despite recent theoretical advances in understanding why individuals within the same population vary in dispersal behavior, relatively few studies have empirically evaluated the long‐term causes and consequences of variable dispersal within natural populations. In this study, we used li...

Black carbon (BC) is an air pollutant of emerging concern, and further evidence is needed to understand its health effects. This study investigates the association between gestational BC exposure and birth outcomes, and whether these effects are independent of particulate matter with an aerodynamic diameter of ≤ 2.5 μm (PM 2.5 ) exposure. We used data from the population-based birth cohort, Maternal Air Pollution in Southern S...