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Introduction Numerous pharmacological classes of compounds have been explored as novel and efficacious alternatives to standard mu opioid agonist analgesics. We and others have described G-protein biased kappa opioid agonists as having potential utility as analgesics due to a lower propensity to produce sedation and dysphoria, which are thought to be mediated in large part through beta-arrestin signaling. Methods Here we compa...
Assessment of biomass and carbon storage of a Populus simonii windbreak located in the Western Cape Province, South AfricaNARA Subscribed
The integration of trees within agricultural systems delivers the opportunity to provide multiple benefits over those afforded by agriculture without trees. The use of windbreaks as a form of agroforestry, in water scarce environments, is primarily used to reduce windspeeds in order to decrease evapotranspiration. Quick growing poplar species such as Populus simonii ((Carrière) Wesm.) are frequently utilised within windbreak s...
Forest models are instrumental for understanding and projecting the impact of climate change on forests. A considerable number of forest models have been developed in the last decades. However, few systematic and comprehensive model comparisons have been performed in Europe that combine an evaluation of modelled carbon and water fluxes and forest structure. We evaluate 13 widely used, state‐of‐the‐art, stand‐scale forest model...