J. Borst results 32
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Characterization of HIV variants from paired Cerebrospinal fluid and Plasma samples in primary microglia and CD4+ T-cellsNARA Subscribed
Despite antiretroviral therapy (ART), HIV persistence in the central nervous system (CNS) continues to cause a range of cognitive impairments in people living with HIV (PLWH). Upon disease progression, transmigrating CCR5-using T-cell tropic viruses are hypothesized to evolve into macrophage-tropic viruses in the CNS that can efficiently infect low CD4-expressing cells, such as microglia. We examined HIV-1 RNA concentration, c...
Paludiculture crops and nitrogen kick-start ecosystem service provisioning in rewetted peat soilsNARA Subscribed
Purpose Paludiculture (crop cultivation in wet peatlands) can prevent carbon and nutrient losses while enabling biomass production. As vegetation in rewetted peatlands is often nitrogen (N) limited, input of N-rich water may promote biomass production and nutrient removal. However, it is unclear how N loading and soil characteristics affect biomass yield, nutrient dynamics, and ecosystem service provisioning in paludiculture....
Human microglial models to study HIV infection and neuropathogenesis: a literature overview and comparative analysesNARA Subscribed
HIV persistence in the CNS despite antiretroviral therapy may cause neurological disorders and poses a critical challenge for HIV cure. Understanding the pathobiology of HIV-infected microglia, the main viral CNS reservoir, is imperative. Here, we provide a comprehensive comparison of human microglial culture models: cultured primary microglia (pMG), microglial cell lines, monocyte-derived microglia (MDMi), stem cell–derived m...
A Systematic Review for the Design of In Vitro Flow Studies of the Carotid Artery BifurcationNARA Subscribed
Purpose In vitro blood flow studies in carotid artery bifurcation models may contribute to understanding the influence of hemodynamics on carotid artery disease. However, the design of in vitro blood flow studies involves many steps and selection of imaging techniques, model materials, model design, and flow visualization parameters. Therefore, an overview of the possibilities and guidance for the design process is beneficial...
Burrowing Crabs Weaken Mutualism Between Foundation SpeciesNARA Subscribed
Neural networks in the cockpit of the flyNARA Subscribed
Contributory presentations/postersNARA Subscribed