To date, research on heat extremes has primarily focused on acute events such as heatwaves. However, many regions of the globe currently face a heat hazard that can persist for months at a time. We call this hazard ‘chronic heat’ and define it here as potentially dangerous heat that lasts for 90 days or more per year. Analyzing 30 years (1993–2023) of global weather station data using three complementary metrics, this study re...

The long‐term success of protected and conserved areas depends on their capacity to remain relevant to human society while maintaining diverse, functional ecosystems. However, despite long‐standing interest in applying complex systems approaches to foster protected area (PA) social–ecological resilience and adaptive capacity, a gap between theory and practice remains. We reviewed the evolution of overarching principles for res...

The release of contaminants into the environment can occur from anthropogenic activities, such as oil extraction and transportation, mining, and industrial processes. Remediation associated with reducing contaminant concentrations, and restoration that improves animals and supporting habitat, are often needed to restore ecosystems to their pre-release, baseline condition. We demonstrated the application of Bayesian Decision Ne...

There is a global increase in the decommissioning of offshore oil and gas (O&G) infrastructure at the end of its operating lifetime. However, there is strikingly limited empirical evidence for the environmental and ecological impacts of decommissioning. Here, we employed a meta‐analytical approach on an industry benthic monitoring database to investigate the benthic biodiversity and food web properties of structures sampled in...

Understanding movement patterns is crucial for predicting species responses to environmental change. However, in aquatic environments, the lack of long-term movement data constrains our ability to interpret how species adapt to changing conditions. Fish otoliths provide insights into individual life-history strategies via time-resolved chemical signatures but disentangling interactions between physiological and environmental p...

Globally, increasing air moisture can limit not only the human body’s ability to cool down, but also that of the Earth’s surface. This interaction, however, remains understudied—especially across subtropical-to-tropical regions that experience high levels of humidity. Here, we examine how air moisture influences nighttime land surface temperatures (LSTs), as well as what this interaction means for thermal comfort overnight. Du...

Consensus has been reached that the sequential loss of biodiversity leads to a non‐linear and accelerating decline in ecosystem properties. The form of this relationship, however, is based on theory and empirically derived observations that do not include species co‐extinctions. Here, we use data from marine benthic invertebrate communities to parameterise trait‐based extinction models that adjust the probability of species ex...

Nomlabofusp is a cell penetrant peptide-based recombinant fusion protein designed to enter cells and deliver human frataxin into the mitochondria of adults and children with Friedreich’s ataxia. In this article we present non-clinical studies evaluating the pharmacology of nomlabofusp, including in a murine striated muscle tissue frataxin knockout model of Friedreich’s ataxia. We demonstrate that subcutaneous administration of...