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Derivation and characterization of an embryonic‑derived muscle progenitor cell line from Atlantic salmon (Salmo salar)NARA Subscribed
Unlike mammals, teleost fish exhibit lifelong skeletal muscle growth, characterized by continued fiber hypertrophy and the formation of new muscle fibers maintained by a persistent progenitor cell population. However, the limited availability of stable muscle progenitor cell lines from commercially important species such as Atlantic salmon ( Salmo salar ) constrains mechanistic studies and emerging applications in cellular aqu...
Best Practices for Performing Analytical and Functional Biosimilarity Assessment of Recombinant Monoclonal Antibody BiosimilarsNARA Subscribed
Biotherapeutic products have revolutionized the diagnosis and treatment of numerous complex to manage diseases, such as cancer, autoimmune disorders, and infectious diseases. When compared with small molecules (pharmaceuticals), this class of therapeutic agents has proven to be more effective and, in general, have fewer side effects. However, they are more expensive (typically 10–1000 times more) and this limits their global a...
Introduction Coral reefs are among the most vital and diverse ecosystems on the planet, providing habitats for marine life, supporting fisheries, and protecting coastlines. However, they are increasingly threatened by outbreaks of Crown-of-Thorns Starfish (COTS), a coral-eating predator capable of causing large-scale reef destruction. Traditional monitoring methods rely on manual diver surveys, which are time-consuming, labour...
Sea cucumbers are widely consumed as a delicacy or in eastern medicine across many Asian countries. Due to the depletion of traditional stocks, new species are increasingly harvested, including the Atlantic sea cucumber (Cucumaria frondosa), the most abundant, cold-water species found in the North Atlantic. This species is harvested in NAFO subdivision 3Ps off the south coast of Newfoundland and Labrador, Canada. As part of th...
Key message Rose has 19 MLO genes. Of these, RhMLO1 and RhMLO2 were shown to be required for powdery mildew infection, which suggests their potential as susceptibility targets towards disease resistance. Abstract Powdery mildew, caused by Podosphaera pannosa , is one of the most serious and widespread fungal diseases for roses, especially in greenhouse-grown cut roses. It has been shown that certain MLO genes are involved in p...
Bioresearches of Fragile Ecosystem/DesertNARA Subscribed