Mitochondrial dysfunction plays a critical role in the development of metabolic dysfunction-associated steatotic liver disease (MASLD). It has been proposed that mitochondrial unfolded-protein response (UPR mt ) activation improves mitochondrial function in the liver. Growing evidence demonstrates that physical exercise effectively prevents and treats MASLD. However, the effects of exercise on UPR mt activation in the liver ar...

Pathogenic fungi that cause rust adversely affect plants, including crops, affecting them differentially depending on the cultivar. This is the case of blackberry ( Rubus spp.), a member of Rosaceae, introduced in Brazil by Embrapa during the 1980s and 1990s. Given the advantageous nutritional properties of its fruits and the relatively low management costs associated with its cultivation, blackberry production has emerged as...

Pleurotus ostreatus is an edible mushroom widely recognized for its nutritional value and high content of bioactive compounds, including phenolics and polysaccharides, which confer potential antidiabetic and anti-obesity effects. These properties are mainly associated with its ability to modulate digestive enzymes involved in carbohydrate and lipid metabolism, as well as its antioxidant activity. This study applied a bioproces...

Aims Ethyl ferulate (EF) may offer novel benefits in hypertension. We investigated the contribution of autonomic receptors to EF-induced effects in female Wistar and SHR. Methods Anesthetized females received EF intravenously at 7.5, 15, or 30 mg/kg. Autonomic involvement was evaluated using pretreatment with atropine, atenolol, or hexamethonium. MAP and HR were continuously monitored. Results EF induced rapid and pronounced r...

Anthropogenic land-use change drives biodiversity loss by altering habitat structure, reducing connectivity, and reshaping ecological processes, even within protected areas. Although protected areas are key for biodiversity conservation, their effectiveness may depend on the surrounding landscape context. This study evaluates the effects of land use around and within protected areas on species richness and functional diversity...

Arboreal small mammals are of particular concern due to their reliance on forest habitats, which are declining, notably in Africa. Most dormice species (Rodentia, Gliridae) are arboreal or semi-arboreal and may serve as indicators of forest habitat quality. However, the ecological requirements of several African dormice species remain poorly understood. We aimed to understand what factors drive the use of microhabitat features...

The Capibaribe and Ipojuca Rivers drain vital watersheds in the state of Pernambuco, northeastern Brazil, but are influenced by intense anthropogenic activities, particularly because they flow through municipalities in the region known as the Textile Triangle. To evaluate the spatial distributions, contamination levels, and sources of trace elements, surface sediments were collected from the two rivers and the concentrations o...