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J. Ebmeyer results 10 · Newest (Page 1/1, per page 25)
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P30-47 Broadening the applicability domain for skin sensitization testing – evaluation of a 3D-Nrf2 reporter epidermis model to test lipophilic compoundsNARA Subscribed
Toxicology Letters · 2025 · Vol. 411 · Elsevier
K. Brandmair; D. Dising; D. Finkelmeier; J. Ebmeyer; T. Rings; E. van Vliet; H. Mizumachi; P. Kern; A. Cuciureanu; D. Allen; J. Kühnl; A. Burger-Kentischer
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P18-01 Implementation and Mechanistic Insights of NAMs for Toxicokinetics and Toxicodynamics Characterization in Next Generation Risk AssessmentNARA Subscribed
Toxicology Letters · 2025 · Vol. 411 · Elsevier
A. Schepky; D. Lange; J. Kuehnl; J. Ebmeyer; M. Boettcher; S. Voss; A. Najjar
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In vitro pharmacologic profiling aids systemic toxicity assessment of chemicalsNARA Subscribed
Toxicology and Applied Pharmacology · 2024 · Vol. 492 · Academic Press
Matthew Burbank; Predrag Kukic; Gladys Ouedraogo; J. Gerry Kenna; Nicola J. Hewitt; Duncan Armstrong; Annie Otto-Bruc; Johanna Ebmeyer; Mareike Boettcher; Ian Willox; Catherine Mahony
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P06-09 Toxicogenomics to analyze systemic toxicity of salicylic acid as part of a NGRA ab initio case studyNARA Subscribed
Toxicology Letters · 2024 · Vol. 399 · Elsevier
S. Voß; K. Brandmair; M. Böttcher; N.J. Hewitt; J. Kuehnl; C.-T. Krüger; D. Lange; J. Meinhardt; A. Najjar; A. Schepky; J. Ebmeyer
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A novel three-dimensional Nrf2 reporter epidermis model for skin sensitization assessmentNARA Subscribed
Toxicology · 2024 · Vol. 503 · Elsevier
K. Brandmair; D. Dising; D. Finkelmeier; A. Schepky; J. Kuehnl; J. Ebmeyer; A. Burger-Kentischer
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Evaluation of new alternative methods for the identification of estrogenic, androgenic and steroidogenic effects: a comparative in vitro/in silico studyNARA Subscribed
Archives of Toxicology · 2024 · Vol. 98 · Issue 1 · Springer
A. Najjar; A. Wilm; J. Meinhardt; N. Mueller; M. Boettcher; J. Ebmeyer; A. Schepky; D. Lange
A suite of in vitro assays and in silico models were evaluated to identify which best detected the endocrine-disrupting (ED) potential of 10 test chemicals according to their estrogenic, androgenic and steroidogenic (EAS) potential compared to the outcomes from ToxCast. In vitro methods included receptor-binding, CALUX transactivation, H295R steroidogenesis, aromatase activity inhibition and the Yeast oestrogen (YES) and Yeast...
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P26-05: Pyrrolizidine alkaloids stimulate different molecular pathways in target organs and verification of in vivo response using human in vitro modelsNARA Subscribed
Toxicology Letters · 2023 · Vol. 384 · Elsevier
J. Buchmueller; J. Ebmeyer; H. Sprenger; M.P. Beckschulte; O. Creutzenberg; D. Schaudien; A. Braeuning; B. Schaefer; S. Hessel-Pras
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P22-06: Development of a 3D Nrf2-ARE reporter skin model for identification of skin sensitizersNARA Subscribed
Toxicology Letters · 2023 · Vol. 384 · Elsevier
J. Ebmeyer; K. Brandmair; D. Dising; D. Finkelmeier; J. Kuehnl; A. Burger-Kentischer
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P09-19: Evaluation of new alternative methods to endocrine disruption: a comparison of in vitro and in silico resultsNARA Subscribed
Toxicology Letters · 2023 · Vol. 384 · Elsevier
D. Lange; A. Najjar; J. Meinhardt; N. Mueller; M. Boettcher; J. Ebmeyer; A. Wilm; A. Schepky
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The pyrrolizidine alkaloid senecionine induces CYP-dependent destruction of sinusoidal endothelial cells and cholestasis in miceNARA Subscribed
Archives of Toxicology · 2020 · Vol. 94 · Issue 1 · Springer
Stefanie Hessel-Pras; Albert Braeuning; Georgia Guenther; Alshaimaa Adawy; Anne-Margarethe Enge; Johanna Ebmeyer; Colin J. Henderson; Jan G. Hengstler; Alfonso Lampen; Raymond Reif
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