In this review, we summarize the data on the cellular pigment lipofuscin that accumulates in liver tissue over time, due to aging and cellular stress. Despite the presence of these typical subcellular inclusions under various conditions, relatively little is known about their origins, roles, and effects on liver cell and tissue health. Pathologists use the presence of lipofuscin, in combination with other markers, to achieve d...

Lipofuscin is a subcellular pigmented granule that has long been considered a sign of wear-and-tear and aging. This granule cannot be degraded but may be diluted by cell division. In the heart, lipofuscin can be easily identified in cardiomyocytes where proliferative capacity is limited, and to a lesser extent in other cardiac cell types, by their characteristic morphological features. They appear as yellow–brown granules in h...

Recent studies have highlighted the ecological importance of cryptic habitat space on coral reefs. These microhabitats, ranging from framework cavities to intra-branch space within marine macroalgae, can harbour diverse and ecologically relevant taxa. Here we show that brittle stars, ubiquitous across such cryptic habitats (reported densities exceeding 100 ind. m −2 ), represent an important, but previously neglected, source o...

Aim Animal movements are a fundamental process affecting communities and ecosystems. Quantifying habitat selection across species and habitats is key for understanding how animals respond to environmental change. Currently, we lack comparative studies that examine how habitat selection varies across species traits and landscapes. We aim to quantify global patterns of habitat selection to help understand the fundamental drivers...

Quantifying animal movements is necessary for answering a wide array of research questions in ecology and conservation biology. Consequently, ecologists have made considerable efforts to identify the best way to estimate an animal's home range, and many methods of estimating home ranges have arisen over the past half a century. Most of these methods fall into two distinct categories of estimators that have only recently been d...

Occasionally, tissue samples cannot be processed completely and are stored under varying conditions for extended periods. This is particularly beneficial in interinstitutional studies where a given research setting may lack the expertise or infrastructure for sample processing, imaging and data analysis. Currently, there is limited literature available on the controlled storage of biological tissues in primary fixatives for fl...

Mouse models are important contributors for understanding the immune system during infections. Objective parameters help to assess the course of infection and guarantee animal welfare. In this study we analyzed if surface temperature measured via thermal imaging of the dorsal area is a suitable marker to evaluate animal wellbeing during murine coronavirus (MCoV) infection. Infected BALB/c mice displayed severe symptoms whereas...

Biotic interactions are expected to influence species' responses to global changes, but they are rarely considered across broad spatial extents. Abiotic factors are thought to operate at larger spatial scales, while biotic factors, such as species interactions, are considered more important at local scales within communities, in part because of the knowledge gap on species interactions at large spatial scales (i.e., the Eltoni...

Cable bacteria are multicellular filamentous microorganisms that perform electrogenic sulphur oxidation over centimetre‐long distances. These filaments contain so‐called “ghost cells”, which display a highly reduced cytoplasmic content and a lack of metabolic activity. However, the origin and abundance of these ghost cells are not well understood, raising questions about their formation and potential impact on the functioning...

Carbonate production by sclerobionts was quantified with calcification‐accretion units (CAUs) to evaluate the roles of different taxonomic groups in the construction and maintenance of coral reef structures in two sites in the Mexican Pacific with contrasting environmental characteristics: Yelapa and Isla Espíritu Santo (IES). Five CAUs were collected every 6 months for 2 years. The average calcification rate in Yelapa and IES...

Subthalamic deep brain stimulation (STN-DBS) is known to improve motor function in advanced Parkinson’s disease (PD) and to enable a reduction of anti-parkinsonian medication. While the levodopa challenge test and disease duration are considered good predictors of STN-DBS outcome, other clinical and neuroanatomical predictors are less established. This study aimed to evaluate, in addition to clinical predictors, the effect of...