J. Firman results 16
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The evaluation of skin sensitization potential of the UVCB substance diisopentyl phthalate by in silico and in vitro methodsNARA Subscribed
Diisopentyl phthalate (DiPeP) is primarily used as a plasticizer or additive within the production of polyvinyl chloride (PVC), and has many additional industrial applications. Its metabolites were recently found in urinary samples of pregnant women; thus, this substance is of concern as relates to human exposure. Depending upon the nature of the alcohol used in its synthesis, DiPeP may exist either as a mixture consisting of...
Adverse outcome pathways (AOPs) were introduced in modern toxicology to provide evidence-based representations of the events and processes involved in the progression of toxicological effects across varying levels of the biological organisation to better facilitate the safety assessment of chemicals. AOPs offer an opportunity to address knowledge gaps and help to identify novel therapeutic targets. They also aid in the selecti...
An environmental resistance model to inform the biogeography of aquatic invasions in complex stream networksNARA Subscribed
Aim Freshwater invasions are a global conservation issue. Emerging tools for biogeographical analyses can provide critical information for their effective management and monitoring. Here, we propose a method to assess the distribution of environmental resistance of stream ecosystems to biological invasions by coupling multi‐stage habitat potential models for non‐native species. Location Andean Patagonia (Chile and Argentina)....
Coherence among Oregon Coast coho salmon populations highlights increasing relative importance of marine conditions for productivityNARA Subscribed
Anadromous fishes, such as Pacific salmon, spend portions of their life cycle in freshwater and marine systems, thus rendering them susceptible to a variety of natural and anthropogenic stressors. These stressors operate at different spatiotemporal scales, whereby freshwater conditions are more likely to impact single populations or subpopulations, while marine conditions are more likely to act on entire evolutionarily signifi...
Limited influence of landscape on the genetic structure of three small mammals in a heterogeneous arid environmentNARA Subscribed
Aim The complexity and biologically challenging nature of arid landscapes can generate high inter‐ and intra‐species diversity, although these biomes remain poorly studied. We investigated whether prominent geomorphic features in an Australian arid landscape had similar influences on patterns of intra‐specific genetic diversity of three small mammals with different distribution and life history traits. Specifically, we tested...
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