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Understanding how genetic variants influence disease risk through molecular mechanisms remains a central challenge in complex disease genetics. Nonsyndromic orofacial clefts (OFCs) exemplify this challenge, with most risk loci residing in non-coding regions. We hypothesized that common genetic variants influence OFC risk by modulating DNA methylation at regulatory elements through methylation quantitative trait loci (meQTLs)....
Spatiotemporal analysis of montado land cover dynamics in southern Portugal: the influence of anthropogenic and natural disturbancesNARA Subscribed
The montado is a traditional agroforestry system in Portugal that combines cork or holm oak trees with pastures and crops. It provides multiple ecosystems services and supports rural livelihoods. However, in recent decades, the montado has faced several threats that have caused its decline and degradation. Here, we analyse the recent changes in montado cover—between 2006 and 2018—and assess the main drivers and processes of ch...
Aim We evaluated how native vegetation cover influences the diversity of arachnid assemblages across multiple spatial scales in major Brazilian ecosystems. Location Brazil (Amazon and Atlantic rainforests, Cerrado savanna and Caatinga dry forest). Taxon Arachnida (Opiliones, Pseudoscorpiones and Scorpiones). Methods We sampled arachnids at 120 sites using active search and litter sifting. Native vegetation cover was quantified...
Sternochetus mangiferae is a pest of mangoes, occurring worldwide in regions where mangoes are cultivated. In Brazil, this insect was first detected in 2014 in Seropédica, Rio de Janeiro, and since then, various measures and studies have been conducted to contain, monitor and potentially eradicate it. Semiochemicals may provide feasible targets to develop sensitive detection and monitoring tools. Therefore, this study aimed to...
Pigments, Chromatophore Structure, and Gene Expression Underlying Colour Polytypy of a Panamanian Poison FrogNARA Subscribed
Colour polytypism represents an example of phenotypic diversification shaped by genetic divergence and ecological pressures. Poison frogs of the genus Oophaga (Dendrobatidae) are highly polytypic in coloration, making them an ideal system for investigating the genetic and physiological basis of colour variation. We examined gene expression, pigment and histological differences across four colour morphs (aquamarine, brown, gree...
Fine‐Scale Bioregionalization in a Complex Island System: A Freshwater Perspective From the Greater AntillesNARA Subscribed
Aim The isolated nature of islands makes them particularly vulnerable to climate change. The freshwater fishes of the Greater Antilles remain understudied and are further threatened by habitat fragmentation and the introduction of exotic invasive species. A practical solution to protect this diversity is to develop a spatially explicit framework to inform conservation actions. We test whether biogeographically significant subr...
Oxygen Minimum Zones (OMZs) are pivotal ocean regions defined by low dissolved oxygen concentrations [DO]. However, biogeochemical variations within OMZs—both laterally and with depth—may select for fundamentally different microbial metabolisms important for ocean biogeochemistry. We used metagenome sequencing to investigate potential differences by specifically targeting biogeochemically‐important features—including the prima...
Geochemistry of the volcano-sedimentary complex of the Algarve Basin (Silves-Ayamonte, SW Iberia)NARA Subscribed
The Volcano-Sedimentary Complex of the Algarve basin (south of the Iberian Peninsula) belongs to the Large Igneous Province of the Central Atlantic Magmatic Province (CAMP), which developed c.200 Ma following the start of the breakup of Pangaea, and preceding the opening of the Atlantic Ocean. This volcanic complex was emplaced in a short period of time in the Lower Jurassic (Hettangian-Sinemurian). It includes subaerial lava...
Coxiella burnetii in ruminants from SomaliaNARA Subscribed
Q fever in humans and coxiellosis in ruminants are caused by Coxiella burnetii , a zoonotic obligate intracellular bacterium. This infection poses significant health and economic risk. Effective control strategies rely on a thorough understanding of their epidemiology. In this study, we examined the prevalence of C. burnetii in 372 ruminants (190 goats, 133 cattle, and 49 sheep) from the Lower Shabelle and Benadir Regions of S...