Mitochondrial dysfunction plays a critical role in the development of metabolic dysfunction-associated steatotic liver disease (MASLD). It has been proposed that mitochondrial unfolded-protein response (UPR mt ) activation improves mitochondrial function in the liver. Growing evidence demonstrates that physical exercise effectively prevents and treats MASLD. However, the effects of exercise on UPR mt activation in the liver ar...

Anthropogenic habitat transformation has led to population declines and increasing isolation of populations of many species, particularly top predators, where small and fragmented populations often experience limited dispersal and reduced genetic diversity. Jaguars ( Panthera onca ), for example, have lost half of their historical range and most populations outside the Amazon biome are small, isolated and highly threatened. He...

Pathogenic fungi that cause rust adversely affect plants, including crops, affecting them differentially depending on the cultivar. This is the case of blackberry ( Rubus spp.), a member of Rosaceae, introduced in Brazil by Embrapa during the 1980s and 1990s. Given the advantageous nutritional properties of its fruits and the relatively low management costs associated with its cultivation, blackberry production has emerged as...

In this work, the environmental occurrence ranges of different European cephalopod species are described for the whole NE Atlantic shelf including the greater North Sea and Baltic Sea. This is done based on the environmental parameters collected in-situ during surveys that caught commercially important cephalopod species (1990–2022). Results are supplemented and compared with information available in the published literature a...

Marine primary production, converting approximately 50 Gt of inorganic carbon into organic carbon per year, is an important component of the global carbon cycle, and a major determinant of past, present and future climate. Large-scale, long-term estimates of marine primary production rely primarily on two types of models: satellite-based models that make extensive use of remote-sensing data, and ecosystem models providing nume...

Controlled release of chemotherapeutic drugs is a key factor in cancer therapy. In this regard, temperature triggered release of drugs offers a precise control over the release within the tumour region, thus avoiding premature drug release and unspecific toxicity. In this work a novel polymeric N-isopropylacrylamide-based nanocarrier was developed to carry and release doxorubicin in response to the natural higher temperature o...

Ostrea edulis, the European flat oyster, was once a widespread economically and ecologically important marine species, but has suffered dramatic declines over the past two centuries. Consequently, there has been a surge in European restoration efforts, many of which focus on restocking as a conservation measure. In this study, we used whole‐genome sequencing (WGS) data to investigate the population structure, demographic histo...

Dispersal ability is a key factor in determining a species' realized niche. However, it remains unclear whether dispersal ability directly, indirectly, or neutrally affects environmental specialization and species' tolerance ranges. Here, we investigate whether, and how, dispersal ability shapes both the realized and fundamental niches. Focusing on plants, invertebrates, and vertebrates in the topographically complex Atlantic...