Relative cerebral blood flow (rCBF), assessed using pulsed arterial spin labeling (pASL) MRI, and the standardized uptake value ratio (SUVr) in early-phase amyloid-PET (ePET) are used as proxies for brain perfusion. These methods have the potential to streamline clinical workflows and reduce the burden on patients by eliminating the need for additional procedures. While both techniques have shown good agreement with the gold s...

Rationale Cannabidiol (CBD) is increasingly used as a sleep aid for insomnia; yet neurocognitive and subjective state effects following daily therapeutic use are unclear. Objectives To measure the effect of daily CBD use on neurocognitive performance and daily subjective mood in a population with primary insomnia. Methods This study used a randomized, placebo-controlled, parallel design incorporating a single-blind placebo run...

All continents, excluding Antarctica and the Artic, have been affected by incursion from alien freshwater fish species. Australia has not been spared. Four hundred and fifty species have now been declared on the ornamental importation list, making management a real challenge. With approximately 25 non-native species documented, Papua New Guinea (PNG) has likely some problems with invasive freshwater fish. Many of these species...

During recent decades, the health of ocean ecosystems and fish populations has been threatened by overexploitation, pollution and anthropogenic‐driven climate change. Due to a lack of long‐term ecological data, we have a poor grasp of the true impact on the diet and habitat use of fishes. This information is vital if we are to recover depleted fish populations and predict their future dynamics. Here, we trace the long‐term die...

We investigated the distributions and targets of nitrergic neurons in the rat stomach, using neuronal nitric oxide synthase (NOS) immunohistochemistry and nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase histochemistry. Nitrergic neurons comprised similar proportions of myenteric neurons, about 30%, in all gastric regions. Small numbers of nitrergic neurons occurred in submucosal ganglia. In total, there were ~ 1...

Central–southern Italy is one of the most suitable areas in the world for tephrostratigraphic studies, owing to the numerous volcanic sources with explosive activity during the Pleistocene. This work presents a systematic investigation of the chemical (trace elements) and isotopic (Sr and Nd) compositions of the main tephra markers within lacustrine sediments of the San Gregorio Magno Basin (Campania, southern Italy). This stu...