J. Needham results 33
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Differentiation grade is highly concordant between matched primary and metastatic colorectal cancerNARA Subscribed
Differentiation grade of colorectal cancers (CRC) is histologically defined by the proportion of the tumour which retains the glandular architecture of the normal colon. Poorly differentiated CRCs display loss of glandular architecture and canonical markers of colonic differentiation and are associated with increased metastatic capacity and poorer prognosis. It is currently unclear whether poorly differentiated cells within a...
The Effect of Sediment Mud Content on Primary Production in Seagrass and Unvegetated Intertidal FlatsNARA Subscribed
As a consequence of anthropogenic activities and climate change, accelerated terrestrial sediment runoff is causing the gradual mudification of soft sediment estuarine habitats worldwide. Increased sediment mud content (< 63 µm) has been recognised to alter seagrass morphology and cause declines in primary production in unvegetated habitats. However, the effect of increased mud content on primary production in seagrass meadows...
Effects of temperament during handling and social rank on the blood biochemical parameters of common eland (Taurotragus oryx)NARA Subscribed
Large herbivores are subject to handling and social stress in captivity. These may affect blood biochemical values, which motivated this research. Twelve healthy common eland ( Taurotragus oryx ) were monitored for 12 months. The animals were handled monthly, and blood samples were collected. Samples from every second month were analysed for 14 blood biochemical parameters. Temperament throughout the handling, as the summation...
Going under: The implications of sea‐level rise and reduced light availability on intertidal primary productionNARA Subscribed
Estuarine intertidal flats are known for high rates of primary production, however, globally these ecosystems are under threat from rising sea‐level and accelerated inputs of terrestrial sediments. These stressors simultaneously alter the duration of submersion/emersion periods and water‐column turbidity impacting seafloor photoperiods. To assess how changes in submergence time and water‐clarity can affect benthic primary prod...
Crown damage can account for over 23% of canopy biomass turnover in tropical forests and is a strong predictor of tree mortality; yet, it is not typically represented in vegetation models. We incorporate crown damage into the Functionally Assembled Terrestrial Ecosystem Simulator (FATES), to evaluate how lags between damage and tree recovery or death alter demographic rates and patterns of carbon turnover. We represent crown d...
Demographic composition, not demographic diversity, predicts biomass and turnover across temperate and tropical forestsNARA Subscribed
The growth and survival of individual trees determine the physical structure of a forest with important consequences for forest function. However, given the diversity of tree species and forest biomes, quantifying the multitude of demographic strategies within and across forests and the way that they translate into forest structure and function remains a significant challenge. Here, we quantify the demographic rates of 1961 tr...
Seamounts provide oases of hard substrate in the deep sea that are frequently associated with locally enhanced biological productivity and diversity. There is now increasing recognition of their ecological and socio-economic importance. However, management strategies for these habitats are constrained not only by limited ecological understanding but by the general public’s understanding of the pressures facing these ecosystems...
Detection of Phthalate Metabolites in Human Amniotic FluidNARA Subscribed
Phthalate Monoesters Levels in the Urine of Young ChildrenNARA Subscribed