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Whole genome resequencing data provide high-resolution conservation insights into population structure and life historyNARA Subscribed
Whole genome resequencing can be a powerful tool for uncovering biological insights and quantifying population genomic metrics relevant to conservation. These insights have the potential to be most profound in secretive or elusive species that are understudied but whose populations may be waning. The western chicken turtle ( Deirochelys reticularia miaria ) is one such example where conservationists are concerned about reporte...
Diets of sculpins ( Myoxocephalus spp.) and Arctic char ( Salvelinus alpinus ) during a spring resource pulse in the Canadian ArcticNARA Subscribed
The Arctic is one of the fastest‐warming marine regions in the world, which is changing the timing of seasonal sea‐ice dynamics. The annual summer breakup of sea‐ice coincides with resource pulses, which provide critical food sources for consumers to exploit. Marine organisms respond behaviourally to exploit these resources, with some migrating to presumably maximize feeding opportunities, whereas others remain resident, provi...
Illegal trade in leopard tortoises Stigmochelys pardalis is widespread, yet the origins of confiscated S. pardalis are often unknown. Accurate assignment to source populations is essential for informed conservation management and release. We expanded and tested a genetic reference database for assigning S. pardalis to their original wild populations in KwaZulu-Natal Province, South Africa, and Eswatini. We added 50 newly genot...
IND-enabling preclinical studies of [11C]COU, a trapped metabolite PET radiotracer for monoamine oxidase-BNARA Subscribed
[ 11 C]COU is a trapped metabolite radiotracer for in vivo analysis of Monoamine Oxidase B activity using positron emission tomography (PET) imaging. [ 11 C]COU has the potential to quantify astrocytosis in the early stages of Alzheimer’s disease, providing an earlier marker of disease than currently available for staging disease progression. Prior preclinical studies have demonstrated the efficacy of this radiotracer in precl...