Ageing is a fundamental biological process marked by declining physiological function and the accumulation of stress-induced damage. It contributes to chronic disease and drives widespread alterations across organ systems, including the vasculature. Ageing of the macro- and microvasculature impairs nutrient delivery, promotes tissue degeneration, and reduces repair capacity in many tissues, including those of the musculoskelet...

Effective conservation practice requires decisions based on reliable and relevant evidence, but significant gaps in the evidence base exist. Incorporating well‐designed tests of the effectiveness of interventions for biodiversity in conservation projects is one of the best ways to scale up the rate of evidence generation. Funders of conservation projects are uniquely positioned to support and incentivize such tests as part of...

Only one last interglacial relative sea‐level indicator point (SLIP) has been recognised for Fenland, eastern England, and the nearest penultimate interglacial SLIP is located on the north Norfolk coast. Such limited information restricts the regional input to, and hence the relevance of, global reconstructions of late Middle and Late Pleistocene sea level. Marine‐influenced deposits without such relevant data are known in Fen...

Aim Widespread species encounter a range of variable climates that can lead to intraspecific trait clines. Such clines can be the result of phenotypic plasticity, genetic differences, or both. Although latitude often explains a large part of trait variation, it is crucial to investigate the underlying environmental variables to understand current and future trait responses. Cross‐continental comparisons of species that are nat...

Research on physical activity (PA) and health has a fundamental concern with dose–response relationships. The variables of (1) Frequency, (2) Intensity, (3) Time, and (4) Type (i.e., the FITT principle) have traditionally been used to operationalize the dosage of PA. We consider some limitations of FITT and propose that it can be complemented by the additional variable density (from the German exercise and training variable Be...