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Opportunities to improve detection of genetic predisposition for ovarian cancer applying the Tumor-First workflowNARA Subscribed
Genetic testing in ovarian carcinoma (OC) patients is very important for patients and their relatives. The Tumor-First workflow uses a tumor DNA test to stratify germline testing for hereditary cancer predisposition as well as treatment options with PARP inhibitors. This workflow is adopted and successfully implemented nationwide. Here, we evaluated recent tumor DNA testing rates in the Netherlands to identify untested OC pati...
Community biocultural mapping reveals historical occupation and enables defense of African rainforestsNARA Subscribed
Global conservation maps often overlook community lands, impacting decision-making and reducing local agency. We focus on the high-profile and regionally important case of Massaha’s ancestral territory (Ibola Dja Bana Ba Massaha). In Gabon, the forest is largely gazetted into logging concessions and described as an Eden-like wilderness despite long-term human presence. We compare Massaha’s biocultural maps to global, colonial,...
Diet of juvenile skipjack herring Alosa chrysochloris : Ontogenetic shifts, predator–prey size ratios and mouth gape allometryNARA Subscribed
The skipjack herring Alosa chrysochloris inhabits Gulf of Mexico drainages, primarily the Mississippi River Basin, and estuarine environments in the Gulf of Mexico. The trophic ecology of the skipjack herring is poorly understood, therefore we quantified the length, mouth gape and gut contents of juvenile skipjack herring from the Mississippi River (fish n = 6), Illinois River (fish n = 181) and Ohio River (fish n = 255) and t...
The Effects of Land‐Use Dynamics on Avian Phylogenetic Diversity Across Island EcosystemsNARA Subscribed
Aim To test whether forest extent and recent forest‐cover change are associated with avian phylogenetic diversity and community‐level evolutionary value across islands. Location Seven islands spanning Borneo and Wallacea in the Malay Archipelago. Taxon Terrestrial birds. Methods We sampled 1410 sites (2010–2022). We calculated phylogenetic diversity (PD), mean phylogenetic distance (MPD), mean nearest taxon distance (MNTD) and...
The Asia region harbors exceptional chondrichthyan (shark, ray, and chimaera) diversity but faces intense fishing pressure. The Important Shark and Ray Areas (ISRA) process provides a collaborative, evidence-based framework to identify critical habitats and inform spatial management. We assessed ISRAs across the Bay of Bengal, Southeast Asia, and the Northwest Pacific to characterize their extent, ecological significance, and...
Introduction Physical activity may enhance cognition in older adults, yet evidence from randomized controlled trials (RCTs) on mechanistic pathways remains inconclusive. Methods This single-blinded RCT examined the effects of an 8-week, online-guided, multicomponent physical activity intervention on cognitive function, resting-state functional brain connectivity (rsFC), and the gut microbiome in 92 healthy older adults (M age...
Diversity and functional group composition drive biogeographic patterns in marine biogenic structural complexityNARA Subscribed
Biogenic structural complexity is a key driver of biodiversity and ecosystem functioning, yet its ecological and environmental determinants remain poorly understood across broad biogeographic scales. Here, we conducted standardized 90‐day field experiments at 16 coastal sites, spanning a 41‐degree latitudinal gradient, using naturally assembled marine fouling communities on settlement panels. We measured rugosity as our metric...
Origins and environmental impacts of distal rhyolitic tephra layers on Chatham Island, New ZealandNARA Subscribed
Chatham Island, ~700 km east of mainland New Zealand, preserves several macroscopic tephra beds, sourced from the central Taupō Volcanic Zone (TVZ) some 850 km away. These layers, often enclosed within peat, provide insights into the eruptive characteristics, timing and paleoenvironmental impacts of large explosive rhyolitic eruptions in a distal setting. We report the nature, origins and impacts of these tephras by documentin...
Local and Landscape‐Level Environmental Conditions Drive Habitat Selection Across Terrestrial Mammal SpeciesNARA Subscribed
Aim Animal movements are a fundamental process affecting communities and ecosystems. Quantifying habitat selection across species and habitats is key for understanding how animals respond to environmental change. Currently, we lack comparative studies that examine how habitat selection varies across species traits and landscapes. We aim to quantify global patterns of habitat selection to help understand the fundamental drivers...
Connectivity is a multifaceted concept that has important implications for the management and conservation of marine and freshwater fishes. We developed a conceptual framework that encompasses multiple, interrelated categories of connectedness, including landscape (e.g., structural, functional) connectivity and ecological (e.g., trophic, genetic, demographic) connectivity, that together shape the flow of organisms, energy and...