Patients with multiple myeloma (MM), patient advocates, healthcare providers (HCPs), and industry sponsors gathered at 2 MM Health Equity Summits to discuss their experiences and perspectives on MM healthcare inequities in the US. Eight topics relevant to the patient experience were identified at the first summit, prioritized by participant survey, and aligned on by the entire group. Two topics were then selected for priority...

Skin is the largest mammalian organ and the first defensive barrier against the external environment. The skin and fur of mammals can host a wide variety of ectoparasites, many of which are phylogenetically diverse, specialized, and specifically adapted to their hosts. Among hematophagous dipteran parasites, volatile organic compounds (VOCs) are known to serve as important attractants, leading parasites to compatible sources o...

Aim There have been numerous studies of forest‐soil microbial biogeography, but an integrated view of edaphic factors, plant, climatic factors, and geographic distance in determining the variation of bacterial community and assembly processes remains unclear at large spatial scales. Here, we analysed the factors affecting the biogeographic pattern and assembly processes of soil bacterial communities under 58 tree species in fi...

The article Microbial Exchange via Fomites and Implications for Human Health, written by Brent Stephens, Parham Azimi, Megan S. Thoemmes, Mohammad Heidarinejad, Joseph G. Allen, and Jack A. Gilbert, was originally published electronically on the publisher’s internet portal

Summary Organic matter application is a widely used practice to increase soil carbon content and maintain soil fertility. However, little is known about the effect of different types of organic matter, or the input of exogenous species from these materials, on soil fungal communities. In this study, fungal community composition was characterized from soils amended with three types of organic matter over a 30‐year fertilization...

Summary The alpha diversity of foliar fungal endophytes ( FEs ) in leaves of B etula ermanii in a subalpine timberline ecotone on C hangbai M ountain, C hina increased with elevation. There were also significant differences in beta diversity along the elevation gradient. Among the environmental variables analysed, leaf carbon significantly increased with elevation, and was the most significant environmental factor that constra...

Summary Soil microbial communities are essential for ecosystem function, but linking community composition to biogeochemical processes is challenging because of high microbial diversity and large spatial variability of most soil characteristics. We investigated soil bacterial community structure in a switchgrass stand planted on soil with a history of grassland vegetation at high spatial resolution to determine whether biogeog...

Summary Microbial community structure, and niche and neutral processes can all influence response to disturbance. Here, we provide experimental evidence for niche versus neutral and founding community effects during a bioremediation‐related organic carbon disturbance. Subsurface sediment, partitioned into 22 flow‐through columns, was stimulated in situ by the addition of acetate as a carbon and electron donor source. This drov...

Summary We reconstructed the complete 2.4 Mb‐long genome of a previously uncultivated epsilonproteobacterium, C andidatus Sulfuricurvum sp. RIFRC ‐1, via assembly of short‐read shotgun metagenomic data using a complexity reduction approach. Genome‐based comparisons indicate the bacterium is a novel species within the S ulfuricurvum genus, which contains one cultivated representative, S . kujiense . Divergence between the speci...

G protein-coupled receptors strongly modulate neuronal excitability but there has been little evidence for G protein mechanisms in genetic epilepsies. Recently, four patients with epileptic encephalopathy (EIEE17) were found to have mutations in GNAO1, the most abundant G protein in brain, but the mechanism of this effect is not known. The GNAO1 gene product, Gα o , negatively regulates neurotransmitter release. Here, we repor...

Summary Very few marine microbial communities are well characterized even with the weight of research effort presently devoted to it. Only a small proportion of this effort has been aimed at investigating temporal community structure. Here we present the first report of the application of high‐throughput pyrosequencing to investigate intra‐annual bacterial community structure. Microbial diversity was determined for 12 time poi...