BACKGROUND : Bone marrow–derived MSCs (BMMSCs) are limited by availability, donor variability, and age-related decline, highlighting the need for alternative MSC sources. Induced pluripotent stem cells (iPSCs) offer a scalable solution. This study introduces a novel three-dimensional culture platform based on fibronectin (FN)-coated microparticles to efficiently derive and expand human iPSC-derived MSCs (iMSCs). METHODS : The...

The mineralization of organic matter at the sediment plays a crucial role in ecosystem functioning by facilitating the biogeochemical cycling of carbon and nutrients. This process not only supports nutrient availability for primary production but also regulates the long-term storage of carbon within sediments. To understand the biogeochemical processes associated with organic matter mineralization and nutrient regeneration, we...