Background Chronic inflammatory pain is associated with persistent sensory and immune dysregulation. We evaluated the therapeutic efficacy of two cannabinoids formulations—Cannabigerol (CBG) and Standardized Full-Spectrum Cannabis Extract (FULL) in a preclinical model of acute and Chronic inflammatory pain and examined their effects on peripheral and central inflammatory mediators. Methods Cannabinoid analgesic effects were as...

The Chicxulub impact ∼66 Ma ago formed a large basin on the Yucatán platform, filled by sediments that provide a record of carbonate deposition, sea level and climate changes in the Gulf of Mexico. We study the post-impact sequence drilled in the Yaxcopoil-1 borehole in the crater terrace zone. The post-impact section is 792 m thick, overlying the impactites and Cretaceous carbonates. Section analyzed is between 400 and 792 m,...

Main Animals not only forage for abundant and nearby resources, but their diets can also be influenced by abiotic and geographic factors. This often results in non‐random interactions among species. We investigate how seed density, distance from nest, abiotic (e.g., climate stability, temperature, precipitation) and geographic factors (e.g., latitude, elevation and continental hemisphere) influence the removal of food items (i...

Aim The transition from the Medieval Climate Anomaly (MCA, 950–1250 CE) to the Little Ice Age (LIA, 1350–1800 CE) is the largest pre‐industrial climate shift within the last two millennia, offering an opportunity to study how vegetation responds to rapid climate change. We analysed a sedimentary record from the Colombian Andes to reconstruct regional vegetation dynamics during this time interval, identify the modern environmen...

Aim Multiple abiotic and biotic factors, mainly the amount and seasonality of precipitation, fire regime, soil properties and species adaptation strategies, have been invoked to explain the existence of the tropical savanna–humid forest transition. We explored the rainfall variables that influence the probability of forest or savanna occurring in north‐west South America, specifically monthly precipitation and the mean and max...

The Colombian Tropical Andes are one of the regions with highest bird diversity on Earth. However, information on bird morphology, reproductive phenology, and molt is particularly scarce in this region. Also, this region is heavily impacted by deforestation, and it is vulnerable to climate change. Hence, providing baseline information on life history and morphological traits will be essential to support future research on func...

Mexico is one of the most biodiverse countries in the world, with an important proportion of endemism mainly because of the convergence of the Nearctic and Neotropical biogeographic regions, which generate great diversity and species turnover at different spatial scales. However, most of our knowledge of the Mexican ant biota is limited to a few well‐studied taxa, and we lack a comprehensive synthesis of ant biodiversity infor...