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NARA Subscribed2
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Elsevier1
Springer Nature1
Journal
Archives of Toxicology1
Mutation Research - Genetic Toxicology and Environmental Mutagenesis1
Publication Year
20242
Jaime Miranda-Colon results 2 · Newest (Page 1/1, per page 25)
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Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutationsNARA Subscribed
Mutation Research - Genetic Toxicology and Environmental Mutagenesis · 2024 · Vol. 897 · Elsevier
Yiying Wang; Yuan Le; Kelly L. Harris; Ying Chen; Xilin Li; Jennifer Faske; Rebecca A. Wynne; Roberta A. Mittelstaedt; Xuefei Cao; Jaime Miranda-Colon; Lana Elkins; Levan Muskhelishvili; Kelly Davis; Nan Mei; Wei Sun; Timothy W. Robison; Robert H. Heflich; Barbara L. Parsons
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Evaluating the mutagenicity of N-nitrosodimethylamine in 2D and 3D HepaRG cell cultures using error-corrected next generation sequencingNARA Subscribed
Archives of Toxicology · 2024 · Vol. 98 · Issue 6 · Springer
Ji-Eun Seo; Yuan Le; Javier Revollo; Jaime Miranda-Colon; Hannah Xu; Page McKinzie; Nan Mei; Tao Chen; Robert H. Heflich; Tong Zhou; Timothy Robison; Jessica A. Bonzo; Xiaoqing Guo
Human liver-derived metabolically competent HepaRG cells have been successfully employed in both two-dimensional (2D) and 3D spheroid formats for performing the comet assay and micronucleus (MN) assay. In the present study, we have investigated expanding the genotoxicity endpoints evaluated in HepaRG cells by detecting mutagenesis using two error-corrected next generation sequencing (ecNGS) technologies, Duplex Sequencing (DS)...
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