James Doherty results 33
· Newest (Page 1/2, per page 25)
Author: James Doherty ×Clear All Filters
Search Results
Remotely Sensed Fire Heterogeneity and Biomass Recovery Predicts Empirical Biodiversity ResponsesNARA Subscribed
Aim To compare field‐based evidence of plant and animal responses to fire with remotely sensed signals of fire heterogeneity and post‐fire biomass recovery. Location South‐eastern Australia; New South Wales. Time Period 2019–2022. Major Taxa Studied A total of 982 species of plants and animals, in eight taxonomic groups: amphibians, birds, fish, insects, mammals, molluscs, plants and reptiles. Methods We collated 545,223 plant...
Rhombencephalosynapsis (RES) is a hindbrain malformation characterized by a missing cerebellar vermis with apposition or fusion of the cerebellar hemispheres. The present clinical case report provides a comprehensive, longitudinal overview of cognitive and affective manifestations in a 22-year-old patient with RES. The patient shows clinical signs of emotional reactivity and dysregulation, impulsivity, and impairments in execu...
Near-term climate risks and sunlight reflection modification: a roadmap approach for physical sciences researchNARA Subscribed
Current impacts and escalating risks of climate change require strong and decisive action to reduce greenhouse gas (GHG) emissions. They also highlight the urgency of research to enhance safety for human and natural systems, especially for those most vulnerable. This is reflected in two recent US National Academies of Science, Engineering, and Medicine studies that recommended a national focus on advancing our understanding of...
Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessmentNARA Subscribed
The receptor tyrosine kinase, MERTK, plays an essential role in homeostasis of the retina via efferocytosis of shed outer nuclear segments of photoreceptors. The Royal College of Surgeons rat model of retinal degeneration has been linked to loss-of-function of MERTK, and together with the MERTK knock-out mouse, phenocopy retinitis pigmentosa in humans with MERTK mutations. Given recent efforts and interest in MERTK as a potent...
Current in vitro genotoxicity tests can produce misleading positive results, indicating an inability to effectively predict a compound’s subsequent carcinogenic potential in vivo. Such oversensitivity can incur unnecessary in vivo tests to further investigate positive in vitro results, supporting the need to improve in vitro tests to better inform risk assessment. It is increasingly acknowledged that more informative in vitro...
Whakamanahia Te mātauranga o te Māori: empowering Māori knowledge to support Aotearoa’s aquatic biological heritageNARA Subscribed
As Aotearoa New Zealand grapples with developing solutions to complex issues surrounding its unique freshwater and marine biological heritage, there is a growing recognition that mātauranga Māori can be ‘unlocked’ and used with great effect alongside western science. Examples where appropriate consideration and development of robust methodologies for the application of mātauranga Māori coexisting alongside western science are...
Motivation The BioTIME database contains raw data on species identities and abundances in ecological assemblages through time. These data enable users to calculate temporal trends in biodiversity within and amongst assemblages using a broad range of metrics. BioTIME is being developed as a community‐led open‐source database of biodiversity time series. Our goal is to accelerate and facilitate quantitative analysis of temporal...