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Standardized microhaplotype databases and frameworks for assessing and mining crop genetic diversityNARA Subscribed
Keymessage Standardized microhaplotype databases for eight diverse crops enable multiallelic analyses, comparative genetics, and breeding decisions. Abstract Microhaplotypes are short genomic segments that contain multiple tightly linked variants, providing multi-allelic data that can enhance genetic resolution compared to traditional biallelic single nucleotide polymorphism (SNP) markers. Here, we present the creation and uti...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Drought, Conflict and the Use of Historical Data and Methodologies in Interdisciplinary Palaeoclimatic ResearchNARA Subscribed
A major challenge in the interdisciplinary study of past climates is ensuring that evidence and data relating to different disciplines are analysed effectively using appropriate methodologies. In ‘Droughts and conflict during the late Roman period’, Clim. Chang 178, 2025, Norman et al. argue that historical sources support their conclusions that drought contributed causally to the ‘barbarian conspiracy’ of 367CE and to other l...
Ethane is the most abundant non-methane hydrocarbon in Earth’s atmosphere and acts as an indirect greenhouse gas, influencing the atmospheric lifetime of methane. Therefore, understanding the development of trends and identifying trend reversals in atmospheric ethane is crucial. Ethane abundance is measured at different ground-based stations worldwide using Fourier transform infrared remote sensing techniques. We compile a new...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Ocean Heat Content Sets Another Record in 2025NARA Subscribed
Global ocean warming continued unabated in 2025 in response to increased greenhouse gas concentrations and recent reductions in sulfate aerosols, reflecting the long-term accumulation of heat within the climate system, with conditions evolving toward La Niña during the year. In 2025, global upper 2000 m ocean heat content (OHC) increased by ∼23 ± 8 ZJ relative to 2024 according to IAP/CAS estimates. CIGAR-RT, and Copernicus Ma...