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NARA Subscribed1
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Springer Nature1
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Journal of NeuroVirology1
Publication Year
20221
Jamie Toombs results 1 · Newest (Page 1/1, per page 25)
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Correlation between cerebrospinal fluid and plasma neurofilament light protein in treated HIV infection: results from the COBRA studyNARA Subscribed
Journal of NeuroVirology · 2022 · Vol. 28 · Issue 1 · Springer
Jasmini Alagaratnam; Davide De Francesco; Henrik Zetterberg; Amanda Heslegrave; Jamie Toombs; Neeltje A. Kootstra; Jonathan Underwood; Magnus Gisslen; Peter Reiss; Sarah Fidler; Caroline A. Sabin; Alan Winston
Cerebrospinal fluid (CSF) neurofilament light protein (NfL) is a marker of central nervous system neuro-axonal injury. A novel, ultra-sensitive assay can determine plasma NfL. In untreated people-with-HIV (PWH), CSF and plasma NfL are strongly correlated. We aimed to assess this correlation in PWH on suppressive antiretroviral treatment (ART) and lifestyle-similar HIV-negative individuals enrolled into the COmorBidity in Relat...
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