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Free Tools—Not So “Free”? The Evolution, Risks and Costs of Fishery Stock Assessment ToolsNARA Subscribed
In fisheries stock assessment, free software tools have proliferated in recent years. These tools provide standardised and, in many cases, well‐tested and efficient ways to conduct and support stock assessments, making cutting edge expertise globally accessible. However, they come with considerable ongoing costs, beyond their conceptual development and coding. We seek to understand and analyse the process by which fisheries st...
Prostate cancer radiation therapy shape variation analysisNARA Subscribed
Fisheries stock assessment capacity faces resource constraints in many countries, including limited personnel, high workloads, and restricted funding. Stock assessment scientists often operate under short timelines, with outcomes that can influence livelihoods and receive public scrutiny. Scientists frequently manage multiple assessments each year, making time management a challenge. Consequently, finding opportunities to inve...
How much data do you need? An analysis of pelvic multi-organ segmentation in a limited data contextNARA Subscribed
Training deep learning models generally requires large, costly datasets which can limit their application towards in-house segmentation tasks. This study investigates the trade-off in dataset size within the context of pelvic multi-organ MR segmentation where we evaluate the performance of nnU-Net, a well-known segmentation model, under conditions of limited domain and data availability. 12 participants undergoing treatment on...
Automatic segmentation of tumour and organs at risk in 3D MRI for cervical cancer radiation therapy with anatomical variationsNARA Subscribed
Cervical cancer is a common cancer in women globally, with treatment usually involving radiation therapy (RT). Accurate segmentation for the tumour site and organ-at-risks (OARs) could assist in the reduction of treatment side effects and improve treatment planning efficiency. Cervical cancer Magnetic Resonance Imaging (MRI) segmentation is challenging due to a limited amount of training data available and large inter- and int...
Prostate volume analysis in image registration for prostate cancer care: a verification studyNARA Subscribed
Combined magnetic resonance imaging (MRI) and positron emission tomography/computed tomography (PET/CT) may enhance diagnosis, aid surgical planning and intra-operative orientation for prostate biopsy and radical prostatectomy. Although PET-MRI may provide these benefits, PET-MRI machines are not widely available. Image fusion of Prostate specific membrane antigen PET/CT and MRI acquired separately may be a suitable clinical a...
Radiation therapy is moving from CT based to MRI guided planning, particularly for soft tissue anatomy. An important requirement of this new workflow is the generation of synthetic-CT (sCT) from MRI to enable treatment dose calculations. Automatic methods to determine the acceptable range of CT Hounsfield Unit (HU) uncertainties to avoid dose distribution errors is thus a key step toward safe MRI-only radiotherapy. This work h...
Clinical validation of MR imaging time reduction for substitute/synthetic CT generation for prostate MRI-only treatment planningNARA Subscribed
Radiotherapy treatment planning based only on magnetic resonance imaging (MRI) has become clinically achievable. Though computed tomography (CT) is the gold standard for radiotherapy imaging, directly providing the electron density values needed for planning calculations, MRI has superior soft tissue visualisation to guide treatment planning decisions and optimisation. MRI-only planning removes the need for the CT scan, but re...
Automatic classification of distal radius fracture using a two-stage ensemble deep learning frameworkNARA Subscribed
Distal radius fractures (DRFs) are one of the most common types of wrist fracture and can be subdivided into intra- and extra-articular fractures. Compared with extra-articular DRFs which spare the joint surface, intra-articular DRFs extend to the articular surface and can be more difficult to treat. Identification of articular involvement can provide valuable information about the characteristics of fracture patterns. In this...
Open-source, fully-automated hybrid cardiac substructure segmentation: development and optimisationNARA Subscribed
Radiotherapy for thoracic and breast tumours is associated with a range of cardiotoxicities. Emerging evidence suggests cardiac substructure doses may be more predictive of specific outcomes, however, quantitative data necessary to develop clinical planning constraints is lacking. Retrospective analysis of patient data is required, which relies on accurate segmentation of cardiac substructures. In this study, a novel model was...
Successful fisheries management systems tend to be underpinned by harvest strategies, specifying formally agreed data collection systems, assessment approaches and management measures used to regulate fishing pressure. While harvest strategies can be effective even in data‐ and capacity‐limited (DCL) situations, their development remains challenging in such contexts. We present a process and decision‐support tool, FishPath, to...
As the world population grows, fisheries practitioners will be under increased pressure to address global challenges in data-limited fisheries management. With a focus on addressing localized and case-specific management needs, we provide a practical guide to the design and development of multi-indicator frameworks for fishery management. In a data-limited context, indicators are observations or estimates of the state of the f...
The majority of the world's fisheries, by number, are data‐poor/limited, and there is a growing body of literature pertaining to approaches to estimate data‐limited stock status. There are at least two drivers for assessing the status of data‐limited fisheries. The first is to try to understand and report on the global or regional status of fisheries across many stocks. The second is to attempt to assess individual data‐limite...
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