Multiple system atrophy (MSA) is a fatal neurodegenerative disease of unknown etiology characterized by widespread aggregation of the protein alpha-synuclein in neurons and glia. Its orphan status, biological relationship to Parkinson’s disease (PD), and rapid progression have sparked interest in drug development. One significant obstacle to therapeutics is disease heterogeneity. Here, we share our process of developing a clin...

This simulation‐based study is an effort to develop design requirements for a hypothetical network of instruments to measure average atmospheric variability over a relatively simple terrain. A dataset of air and soil temperature, relative humidity, wind speed, and soil moisture from the vicinity of Lincoln, Nebraska, was used to simulate atmospheric daily measurements (max and min temperature as well as infra‐red surface tempe...