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Springer Nature2
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GeroScience1
Molecular Neurobiology1
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20251
20221
Jerry R. Colca results 2 · Newest (Page 1/1, per page 25)
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Extension of lifespan by epicatechin, halofuginone and mitoglitazone in male but not female genetically heterogeneous miceNARA Subscribed
GeroScience · 2025 · Vol. 48 · Issue 3 · Springer
Randy Strong; James F. Nelson; Molly A. Bogue; Jerry R. Colca; Martin Denzel; Vivian Diaz; Brian N. Finck; Vadim N. Gladyshev; Steve Horvath; Nisi Jiang; Tracy Keller; Rolf F. Kletzien; Ron Korstanje; Navasuja Kumar; Christiaan Leeuwenburgh; Elizabeth Fernandez; Andrzej Galecki; Brett Ginsburg; Melissa Han; Catherine Kaczorowski; Scott Leiser; Marisa Lopez-Cruzan; Ken Raj; Peter C. Reifsnyder; Nadia A. Rosenthal; Susanna Rosi; Anastasia Shindyapina; Peter Stacpoole; Adam B. Salmon; Alexander Tyshkovskiy; Peter Walter; Malcolm Whitman; Richard A. Miller; David E. Harrison
Mice bred in 2021 were tested by the Interventions Testing Program (ITP) for possible lifespan benefits of 2BAct (2BA), dichloroacetate (DCA), Epicatechin (EPI), Forskolin (FSK), Halofuginone (HAL) and Mitoglitazone (MIT). All agents were administered in the diet ad libitum beginning at 7 months of age. In male mice, EPI increased median lifespan by ~ 5%, and HAL and MIT each increased median lifespan by ~ 9%. EPI and HAL, but...
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Re-routing Metabolism by the Mitochondrial Pyruvate Carrier Inhibitor MSDC-0160 Attenuates Neurodegeneration in a Rat Model of Parkinson’s DiseaseNARA Subscribed
Molecular Neurobiology · 2022 · Vol. 59 · Issue 10 · Springer
David Mallet; Raphael Goutaudier; Emmanuel L. Barbier; Sebastien Carnicella; Jerry R. Colca; Florence Fauvelle; Sabrina Boulet
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