Singapore grouper iridovirus (SGIV) is a major viral pathogen threatening grouper aquaculture. The lack of specific antiviral drugs underscores the urgent need to develop safe and effective control strategies. This study demonstrates that tannic acid (TA) exhibits significant anti‐SGIV activity in vitro. In grouper spleen (GS) cells, TA inhibited SGIV replication in a concentration‐dependent manner. Time‐of‐addition assays con...

Singapore grouper iridovirus (SGIV) is a highly pathogenic virus that causes substantial economic losses in marine grouper aquaculture, and effective antiviral agents are currently lacking. In this study, the anti‐SGIV activity of epigallocatechin gallate (EGCG), a natural compound from green tea, was evaluated and its underlying mechanisms were investigated. Cytotoxicity assays showed that EGCG at concentrations up to 12.5 μg...

In the context of the rapid development of computer hardware and the continuous improvement of the artificial intelligence and deep learning theory, aiming at the traditional numerical solution method to solve the underwater acoustic fluctuation equation with large computational volume and the limitation of using various acoustic propagation models. We use the numerical solution calculated by the KRAKEN based on the normal mod...

The integration of weather and climate prediction represents the current frontier in the development of numerical modeling in China. Dynamic downscaling serves as a pivotal approach, improving the performance and resolution of global climate models to the weather scale. Focusing on the ‘23.7’ extreme rainstorm (July 29, 00:00–August 2, 00:00 UTC) in the Beijing‐Tianjin‐Hebei region, this study assesses predictions from the Chi...