Purpose Drug-induced long QT interval syndrome (LQTS) is a risk for Torsade de Pointes (TdP) arrhythmia. The purpose was to investigate patients diagnosed with TdP in relation to dispensed risk drugs, the presence of comorbidities, and sex-differences. Methods All patients with a first episode of a registered TdP diagnosis in the National Patient Register between 2006 and 2018 were included in this register-based cohort study....

Purpose To study the association between the use of drugs for hypertension or heart failure, particularly diuretics, and risk of death in COVID-19. Methods We conducted a cohort study, based on record linked individual-based data from national registers, of all Swedish inhabitants 50 years and older ( n = 3,909,321) at the start of the first SARS-CoV-2 wave in Sweden. The association between use of angiotensin-converting enzym...

Purpose To investigate the prevalence and initiation of statins as well as treatment intensity in the oldest old, with younger olds as a reference. Methods A population-based cohort was used, including record-linked data from the Total Population Register, the Swedish Prescribed Drug Register, and the Swedish Patient Register. In each year over the study period (2009–2015), statin use was described in individuals 85 years or o...