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Springer Nature24
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Journal of Pharmacokinetics and Pharmacodynamics14
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Johan Gabrielsson results 24 · Newest (Page 1/1, per page 25)
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Exposure-response modeling improves selection of radiation and radiosensitizer combinationsNARA Subscribed
Journal of Pharmacokinetics and Pharmacodynamics · 2022 · Vol. 49 · Issue 2 · Springer
Tim Cardilin; Joachim Almquist; Mats Jirstrand; Astrid Zimmermann; Floriane Lignet; Samer El Bawab; Johan Gabrielsson
A central question in drug discovery is how to select drug candidates from a large number of available compounds. This analysis presents a model-based approach for comparing and ranking combinations of radiation and radiosensitizers. The approach is quantitative and based on the previously-derived Tumor Static Exposure (TSE) concept. Combinations of radiation and radiosensitizers are evaluated based on their ability to induce...
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Challenge model of TNFα turnover at varying LPS and drug provocationsNARA Subscribed
Journal of Pharmacokinetics and Pharmacodynamics · 2019 · Vol. 46 · Issue 3 · Springer
Felix Held; Edmund Hoppe; Marija Cvijovic; Mats Jirstrand; Johan Gabrielsson
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Modelling of oscillatory cortisol response in horses using a Bayesian population approach for evaluation of dexamethasone suppression test protocolsNARA Subscribed
Journal of Pharmacokinetics and Pharmacodynamics · 2019 · Vol. 46 · Issue 1 · Springer
Felix Held; Carl Ekstrand; Marija Cvijovic; Johan Gabrielsson; Mats Jirstrand
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Michaelis-Menten from an In Vivo Perspective: Open Versus Closed SystemsNARA Subscribed
The AAPS Journal · 2018 · Vol. 20 · Issue 6 · Springer
Johan Gabrielsson; Lambertus A. Peletier
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New Equilibrium Models of Drug-Receptor Interactions Derived from Target-Mediated Drug DispositionNARA Subscribed
The AAPS Journal · 2018 · Vol. 20 · Issue 4 · Springer
Lambertus A. Peletier; Johan Gabrielsson
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Impact of mathematical pharmacology on practice and theory: four case studiesNARA Subscribed
Journal of Pharmacokinetics and Pharmacodynamics · 2018 · Vol. 45 · Issue 1 · Springer
Lambertus A. Peletier; Johan Gabrielsson
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Modeling of free fatty acid dynamics: insulin and nicotinic acid resistance under acute and chronic treatmentsNARA Subscribed
Journal of Pharmacokinetics and Pharmacodynamics · 2017 · Vol. 44 · Issue 3 · Springer
Robert Andersson; Tobias Kroon; Joachim Almquist; Mats Jirstrand; Nicholas D. Oakes; Neil D. Evans; Michael J. Chappel; Johan Gabrielsson
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Pharmacokinetic Steady-States Highlight Interesting Target-Mediated Disposition PropertiesNARA Subscribed
The AAPS Journal · 2017 · Vol. 19 · Issue 3 · Springer
Johan Gabrielsson; Lambertus A. Peletier
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Erratum to: Tumor Static Concentration Curves in Combination TherapyNARA Subscribed
The AAPS Journal · 2017 · Vol. 19 · Issue 2 · Springer
Tim Cardilin; Joachim Almquist; Mats Jirstand; Alexandre Soselly; Christiane Amendt; Samer El Bawab; Johan Gabrielsson
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Tumor Static Concentration Curves in Combination TherapyNARA Subscribed
The AAPS Journal · 2017 · Vol. 19 · Issue 2 · Springer
Tim Cardilin; Joachim Almquist; Mats Jirstrand; Alexandre Sostelly; Christiane Amendt; Samer El Bawab; Johan Gabrielsson
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Pattern Recognition in Pharmacodynamic Data AnalysisNARA Subscribed
The AAPS Journal · 2016 · Vol. 18 · Issue 1 · Springer
Johan Gabrielsson; Stephan Hjorth
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Pattern Recognition in Pharmacokinetic Data AnalysisNARA Subscribed
The AAPS Journal · 2016 · Vol. 18 · Issue 1 · Springer
Johan Gabrielsson; Bernd Meibohm; Daniel Weiner
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Mixed Effects Modeling Using Stochastic Differential Equations: Illustrated by Pharmacokinetic Data of Nicotinic Acid in Obese Zucker RatsNARA Subscribed
The AAPS Journal · 2015 · Vol. 17 · Issue 3 · Springer
Jacob Leander; Joachim Almquist; Christine Ahlström; Johan Gabrielsson; Mats Jirstrand
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Modeling energy intake by adding homeostatic feedback and drug interventionNARA Subscribed
Journal of Pharmacokinetics and Pharmacodynamics · 2015 · Vol. 42 · Issue 1 · Springer
Peter Gennemark; Stephan Hjorth; Johan Gabrielsson
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A modeling approach for compounds affecting body compositionNARA Subscribed
Journal of Pharmacokinetics and Pharmacodynamics · 2013 · Vol. 40 · Issue 6 · Springer
Peter Gennemark; Rasmus Jansson-Löfmark; Gina Hyberg; Maria Wigstrand; Dorota Kakol-Palm; Pernilla Håkansson; Daniel Hovdal; Peter Brodin; Maria Fritsch-Fredin; Madeleine Antonsson; Karolina Ploj; Johan Gabrielsson
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Feedback modeling of non-esterified fatty acids in obese Zucker rats after nicotinic acid infusionsNARA Subscribed
Journal of Pharmacokinetics and Pharmacodynamics · 2013 · Vol. 40 · Issue 6 · Springer
Christine Ahlström; Tobias Kroon; Lambertus A. Peletier; Johan Gabrielsson
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Challenges of a mechanistic feedback model describing nicotinic acid-induced changes in non-esterified fatty acids in ratsNARA Subscribed
Journal of Pharmacokinetics and Pharmacodynamics · 2013 · Vol. 40 · Issue 4 · Springer
Christine Ahlström; Lambertus A. Peletier; Johan Gabrielsson
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Dynamics of target-mediated drug disposition: characteristic profiles and parameter identificationNARA Subscribed
Journal of Pharmacokinetics and Pharmacodynamics · 2012 · Vol. 39 · Issue 5 · Springer
Lambertus A. Peletier; Johan Gabrielsson
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Feedback modeling of non-esterified fatty acids in rats after nicotinic acid infusionsNARA Subscribed
Journal of Pharmacokinetics and Pharmacodynamics · 2011 · Vol. 38 · Issue 1 · Springer
Christine Ahlström; Lambertus A. Peletier; Rasmus Jansson-Löfmark; Johan Gabrielsson
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MDMA: On the translation from rodent to human dosingNARA Subscribed
Psychopharmacology · 2009 · Vol. 204 · Issue 2 · Springer
A. Richard Green; Johan Gabrielsson; Charles A. Marsden; Kevin C. F. Fone
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A Flexible Nonlinear Feedback System That Captures Diverse Patterns of Adaptation and ReboundNARA Subscribed
The AAPS Journal · 2008 · Vol. 10 · Issue 1 · Springer
Johan Gabrielsson; Lambertus A. Peletier
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A Pharmacodynamic Turnover Model Capturing Asymmetric Circadian Baselines of Body Temperature, Heart Rate and Blood Pressure in Rats: Challenges in Terms of Tolerance and Animal-handling EffectsNARA Subscribed
Journal of Pharmacokinetics and Pharmacodynamics · 2005 · Vol. 32 · Issue 5-6 · Springer
Björn Sällström; Sandra A. G. Visser; Tomas Forsberg; Lambertus A. Peletier; Ann-Christine Ericson; Johan Gabrielsson
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A Dynamical Systems Analysis of the Indirect Response Model with Special Emphasis on Time to Peak ResponseNARA Subscribed
Journal of Pharmacokinetics and Pharmacodynamics · 2005 · Vol. 32 · Issue 3-4 · Springer
Lambertus A. Peletier; Johan Gabrielsson; Jacintha den Haag
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Gastric Acid Secretion in the Dog: A Mechanism-Based Pharmacodynamic Model for Histamine Stimulation and Irreversible Inhibition by OmeprazoleNARA Subscribed
Journal of Pharmacokinetics and Pharmacodynamics · 2002 · Vol. 29 · Issue 4 · Springer
Angela Äbelö; Björn Holstein; Ulf G. Eriksson; Johan Gabrielsson; Mats O. Karlsson
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