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NARA Subscribed1
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Springer Nature1
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Pharmaceutical Research1
Publication Year
20191
John Ferbas results 1 · Newest (Page 1/1, per page 25)
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Functional and Nonclinical Similarity of ABP 980, a Biosimilar of TrastuzumabNARA Subscribed
Pharmaceutical Research · 2019 · Vol. 36 · Issue 12 · Springer
Shea Jassem; Wei Wang; Heather Sweet; Raffi Manoukian; Vincent Chow; Palanisamy Kanakaraj; Katariina M. Hutterer; Scott Kuhns; Ian N. Foltz; Qing Chen; John Ferbas; Helen J. McBride
Purpose The in vitro and in vivo pharmacologic assessment of ABP 980 similarity to its reference product is intended to compare the activity of ABP 980 and trastuzumab and support the overall conclusion of similarity based on a comprehensive analytical and functional evaluation. Methods This work complements the primary assessment of functional similarity with additional in vitro assays, binding studies, and non-clinical studi...
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