John Griffith results 97
· Newest (Page 1/4, per page 25)
Author: John Griffith ×Clear All Filters
Search Results
Habitat fragmentation is a key driver of reduced genetic connectivity and loss of genetic variation among populations, elevating the risk of inbreeding depression and reduced adaptive potential. The black-throated finch ( Poephila cincta ) is an endemic Australian finch with two recognised subspecies, a northern ( P. c. atropygialis ) and southern form ( P. c. cincta ) separated by a biogeographic barrier in northern Australia...
Neurobiology of co-morbid stress and a western diet in mice: mitochondrial, proteomic and behavioral outcomesNARA Subscribed
Chronic stress (CS) and hyper-caloric diets promote affective disorders, however pathobiological interactions await definition. Neurobiological and behavioral influences of chronic stress (CS; 2 h/day restraint for 2 wks) were studied in male C57Bl/6 mice fed a control diet (CD; 12% kcal as fat/65% carbohydrate/23% protein) or Western diet (WD; 32% kcal fat/57% carbohydrate/11% protein) for 20 wks. CS induced weight loss and a...
The Critical Role of Coefficients: Updating Allometric Normalisation Constants for Modern Ecology and ModellingNARA Subscribed
Allometry, the scaling of traits or biological rates with body mass, is central to a wide range of ecological research including dynamic food web modelling. There has been extensive focus on exponents (3/4 scaling laws), but little on the coefficients (normalisation constants). Coefficients that have been used since 2006 are derived from limited data and dated methodologies. Here, we compiled a data set of over 1000 genera wit...
Voxel-wise insights into early Alzheimer’s disease pathology progression: the association with APOE and memory declineNARA Subscribed
Longitudinal investigation of the Apolipoprotein E (APOE) genotype’s impact on Alzheimer’s disease (AD) biomarker progression, focusing on amyloid beta (Aβ) accumulation and gray matter (GM) atrophy, integrating cognitive decline and baseline levels. Longitudinal florbetapir-PET and T1-weighted MRI data from 100 cognitively normal (CN) and mild cognitive impaired (MCI) participants both with considerable global Aβ accumulation...
Generalist predator populations often surge during resource pulses but decline sharply afterwards and shift to alternative prey sources, which experience elevated predation rates. Understanding these numerical and functional responses of predators to resource pulses is especially important for effectively managing island ecosystems, where invasive mammals are generalist predators and vulnerable indigenous birds are alternative...
Complementary value of molecular, phenotypic, and functional aging biomarkers in dementia predictionNARA Subscribed
DNA methylation age (MA), brain age (BA), and frailty index (FI) are putative aging biomarkers linked to dementia risk. We investigated their relationship and combined potential for prediction of cognitive impairment and future dementia risk using the ADNI database. Of several MA algorithms, DunedinPACE and GrimAge2, associated with memory, were combined in a composite MA alongside BA and a data-driven FI in predictive analyse...
Wind dispersed tree species have greater maximum heightNARA Subscribed
Aim We test the hypothesis that wind dispersal is more common among emergent tree species given that being tall increases the likelihood of effective seed dispersal. Location Americas, Africa and the Asia‐Pacific. Time period 1970–2020. Major taxa studied Gymnosperms and Angiosperms. Methods We used a dataset consisting of tree inventories from 2821 plots across three biogeographic regions (Americas, Africa and Asia‐Pacific),...
Exposure to Sublethal Concentrations of Lead (Pb) Affects Ecologically Relevant Behaviors in House Sparrows (Passer domesticus)NARA Subscribed
Global contamination of environments with lead (Pb) poses threats to many ecosystems and populations. While exposure to Pb is toxic at high concentrations, recent literature has shown that lower concentrations can also cause sublethal, deleterious effects. However, there remains relatively little causal investigation of how exposure to lower concentrations of environmental Pb affects ecologically important behaviors. Behaviors...