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Non‐native pink salmon Oncorhynchus gorbuscha carcasses benefit native benthic macroinvertebratesNARA Subscribed
The invasion of the North Atlantic by pink salmon Oncorhynchus gorbuscha has raised concerns regarding their impact on coastal rivers. Although the influence of marine‐derived nutrients from returning adult O. gorbuscha on rivers in their native range has received much attention, the ecological consequences of invasive O. gorbuscha for ecosystems outside the native range are largely unknown. To investigate the impact on the de...
Seasonal differences in predation risk among seagrass epifauna species stabilize community‐level predation over timeNARA Subscribed
Predation risk varies through space and time due to changing refuge quality, predator communities, and prey traits. Despite this, ecological research is often focused on measuring average predation risk at the community level. While this can give important information about overall trophic transfer and ecological efficiency, it ignores differences in predation risk among prey species within a community, which may be important...
Diversity and functional group composition drive biogeographic patterns in marine biogenic structural complexityNARA Subscribed
Biogenic structural complexity is a key driver of biodiversity and ecosystem functioning, yet its ecological and environmental determinants remain poorly understood across broad biogeographic scales. Here, we conducted standardized 90‐day field experiments at 16 coastal sites, spanning a 41‐degree latitudinal gradient, using naturally assembled marine fouling communities on settlement panels. We measured rugosity as our metric...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
SNAPSHOT USA 2024: Year 6 of the Coordinated National Camera Trap Survey of the United StatesNARA Subscribed
Motivation SNAPSHOT USA is an annual, multi‐contributor camera trap survey of mammals across the United States. The growing SNAPSHOT USA dataset is intended for tracking the spatial and temporal responses of mammal populations to changes in land use, land cover and climate. These data will be useful for exploring the drivers of spatial and temporal changes in relative abundance and distribution, as well as the impacts of speci...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Waveforms from Nuclear Explosions (WFNE) RepositoryNARA Subscribed
A key element of successful nuclear monitoring involves the assessment of any newly acquired data in the light of the vast amount of data previously recorded from historical nuclear explosions. To support this effort, the “Waveforms From Nuclear Explosions (WFNE)” repository was developed and is maintained by Leidos under sponsorship of the Defense Threat Reduction Agency (DTRA) to provide convenient access to such historical...
NCBI Orthologs: Public Resource and Scalable Method for Computing High-Precision Orthologs Across Eukaryotic GenomesNARA Subscribed
Orthologs are fundamental for enabling comparative genomics analyses that further our understanding of eukaryotic biology. The unprecedented increase in the availability of high-quality eukaryotic genomes necessitates scalable and accurate methods for orthology inference. The National Center for Biotechnology Information (NCBI) developed “NCBI Orthologs”, a resource and a computational pipeline designed to meet this challenge...
The Holocene history of Australia's climate is surprisingly poorly understood. This is, in part, because of the relatively weak forcing of Holocene climate versus that of the late Pleistocene. However, it is commonly suggested that eastern Australia dried during the mid‐ to late‐Holocene and that this was in response to increased activity in the El Niño–Southern Oscillation (ENSO), in particular, the intensification of the El...
Technical Considerations of Pharmacokinetic Assays for LNP-mRNA Drug Products by RT-qPCRNARA Subscribed
Lipid nanoparticle-messenger RNA (LNP-mRNA) drug products are a growing class of drug modalities. The unique composition of these drug products requires multiple measurements to account for the different components of these drug modalities. Pharmacokinetic (PK) measurements include measurement of the encapsulated mRNA and components of the LNP in circulation to understand the effectiveness of the therapeutic mRNA. The PK measu...
Bridging social and ecological science to create spatially explicit models of human-caused mortality of carnivoresNARA Subscribed
Research indicates that human-caused mortality (HCM) is a key factor limiting numerous large carnivore populations. However, efforts to represent HCM in spatially explicit models have generally been limited in scope—often relying on proxies, such as road or human density. Yet such efforts fail to distinguish different sources of HCM, which can arise from different antecedent processes. We offer a systems-based conceptual frame...
The Night Parrot is a critically endangered nocturnal bird of Australia's arid zone. The species was “lost” for most of the 20th century until its rediscovery in 1990. Extant populations are now known in eastern and western Australia, but the species has been extirpated from much of its historical range. Here we estimate critically needed Essential Biodiversity Variables (EBVs) for the Night Parrot from historical and opportun...
Plasticity and Adaptation of Northern California Eelgrass in Response to Sediment ConditionsNARA Subscribed
Considerable research describes the interactions between seagrasses and their sedimentary environment, but there is little information on how populations differ in their innate versus plastic responses to these differences. Here, we test whether sediment contributes to eelgrass population differentiation and the nature of plastic responses to different sediment environments. We do this via a 15-week, fully crossed common garde...