Precipitation in Lesotho is highly spatially variable, a feature of the high altitude and rugged topography. The hydroclimate dynamics, despite being critical to the water security of Lesotho and adjacent South Africa, are poorly understood. Ratios of oxygen and hydrogen isotopes in meteoric water are excellent tracers of hydroclimatic processes. This study presents the first analysis of stable isotopes from surface waters in...

Apolipoprotein ( APOE ) e4 genotype is an accepted risk factor for accelerated cognitive aging and dementia, though its neurostructural substrates are unclear. The deleterious effects of this genotype on brain structure may increase in magnitude into older age. This study aimed to investigate in UK Biobank the association between APOE e4 allele presence vs. absence and brain imaging variables that have been associated with wor...

The oxygen isotope composition of diatom silica ( δ 18 O diatom ) provides valuable information for palaeoclimate studies where carbonate proxies are either rare or absent in many lakes and ocean sediments. Unfortunately, mineral and rock fragments found alongside diatoms in most sediments can be problematic as the method used will liberate oxygen from all components within the sediment, producing both high‐frequency noise and...